ArticlePediatric radiology2025
Comparing magnetic resonance enterography and endoscopy findings to the motility of magnetic resonance imaging in pediatric Crohn's disease.
Article in Pediatric radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- The Evolving Role of Cine MRI in Crohn's Disease: From Functional Motility Analysis to Precision Management: A Review of the Last 10 Years.Diagnostics (Basel, Switzerland) · 2025Review
Corrections and comments
- Erratum issued
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundQuantitative magnetic resonance imaging (MRI) can evaluate bowel motility in children with Crohn's disease. As inflammation increases, motility decreases.
objectiveOur aim was to show that quantitative MRI correlates with magnetic resonance enterography (MRE). We hypothesize that the motility score will inversely correlate with the Endoscopic Biopsy Acute Histologic Inflammatory Score (eAIS), the Crohn's Disease Endoscopic Index of Severity (CDEIS) score, and the MR Index of Activity (MaRIA) score. MATERIALS AND
methodsThis was a retrospective study of 50 pediatric patients with ileal and/or cecal Crohn's disease who underwent endoscopy and MRE within 7 days of each other without exposure to therapy. Cine images were used from patients' previously obtained MREs to obtain a motility score using GIQuant (Motilent, London, UK). The relationships between the motility score and MaRIA, eAIS, and CDEIS were then calculated by Spearman's rank correlation coefficient (ρ).
resultsThe MaRIA and motility scores inversely correlated (ρ=-0.66, 95%CI (-0.79, -0.46), P<0.0001). MaRIA positively correlated with CDEIS (ρ=0.30, 95%CI (0.02, 0.53), P=0.03) and eAIS (ρ=0.26, 95%CI (0.02, 0.50), P=0.07). The motility score showed a non-significant negative correlation with CDEIS (ρ=-0.17, 95%CI (-0.43, -0.12), P=0.24) and eAIS (ρ=-0.23, 95%CI (-0.48, -0.05), P=0.11).
conclusionQuantitative MRI correlates with standard MRE in identifying inflammation of the bowel in Crohn's disease. The cine image used to produce a motility score is obtained faster than standard MRE and does not require the use of intravenous contrast, a spasmolytic agent, and breath-holding techniques.
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