Evidence map›Paper›PMID 39776188›Full record

ArticleInternational urogynecology journal2025

Pelvic Organ Prolapse Repair Using Robotic-Assisted Sacral Hysterocolpopexy vs Vaginal Surgery with the Uphold™ System: 1-Year Clinical Outcomes.

Georgios Poutakidis, Christian Falconer, Daniel Altman, Ulrika Johannesson, Anju Zhang, Charlotta Ericson, Mats Stenberg, Sabine Altrock, Edward Morcos

Abstract readMulticenter StudyComparative Study
In one paragraph

Article in International urogynecology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Georgios PoutakidisDepartment of Clinical Sciences, Division of Obstetrics and Gynecology, Karolinska Institutet Danderyd Hospital, SE- 182 88, Stockholm, Sweden.
Christian FalconerDepartment of Clinical Sciences, Division of Obstetrics and Gynecology, Karolinska Institutet Danderyd Hospital, SE- 182 88, Stockholm, Sweden.
Daniel AltmanDepartment of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Ulrika JohannessonDepartment of Clinical Sciences, Division of Obstetrics and Gynecology, Karolinska Institutet Danderyd Hospital, SE- 182 88, Stockholm, Sweden.
Anju ZhangDepartment of Clinical Sciences, Division of Obstetrics and Gynecology, Karolinska Institutet Danderyd Hospital, SE- 182 88, Stockholm, Sweden.
Charlotta EricsonDepartment of Clinical Science and Education, Södersjukhuset, Karolinska Institutet and the Division of Obstetrics and Gynecology at Södersjukhuset, Stockholm, Sweden.
Mats StenbergDepartment of Obstetrics and Gynecology, Västerås Central Hospital, Västerås, Sweden.
Sabine AltrockDepartment of Obstetrics and Gynecology, Västerås Central Hospital, Västerås, Sweden.
Edward MorcosDepartment of Clinical Sciences, Division of Obstetrics and Gynecology, Karolinska Institutet Danderyd Hospital, SE- 182 88, Stockholm, Sweden. edward.morcos@regionstockholm.se.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisThe aim of the study was to compare clinical outcomes when using robotic-assisted sacral hysterocolpopexy (RASC) and vaginal surgery using the Uphold™ Vaginal Support System mesh for pelvic organ prolapse repair.

methodsThis was a nonrandomized, prospective, multicenter study in which 72 women underwent RASC, and 73 Uphold™ surgery, for apical prolapse (POP-Q C ≥ stage II). Anatomical outcomes were assessed using the Pelvic Organ Prolapse Quantification (POP-Q) system. Subjective outcomes were evaluated using the Pelvic Floor Distress Inventory 20 (PFDI-20), the Pelvic Floor Impact Questionnaire - short form (PFIQ-7), and the Pelvic Organ Prolapse/Urinary Incontinence Sexual Questionnaire (PISQ-12), as well as pain estimation using the visual analog scale (0-10).

resultsOne year after surgery, an optimal apical segment outcome (POP-Q C stage 0-1) was achieved in 96.4% and 93.3% for the RASC and Uphold™ respectively, p = 0.49. However, reoperation for prolapse recurrence was significantly more common after RASC (11 out of 72 [15.3%] vs Uphold™ (2 out of 71 [2.8%], p = 0.005), and an optimal outcome of the anterior vaginal wall was higher after Uphold™ (p < 0.001). Postoperative PFDI-20, PFIQ-7, and pain significantly improved for both RASC and Uphold™ (p = 0.004 to < 0.001), but a more pronounced improvement in the total PFDI-20 and POPDI-6 sub-scores was observed after Uphold™ than after RASC (-73 ± 55.6 vs -49.2 ± 43.7, p = 0.005 and -39.6 ± 23.6 vs -27 ± 23.9, p < 0.001 respectively).

conclusionsReoperation for prolapse recurrence within 1 year was more common after RASC than after Uphold™. However, the rate of complications was low overall and there were few and largely insignificant differences in outcomes when comparing RASC and Uphold™.

Indexed as

Gynecologic Surgical ProceduresPelvic Organ ProlapseRobotic Surgical ProceduresVaginaAgedFemaleHumansMiddle AgedProspective StudiesRecurrenceReoperationSacrumSurgical MeshSurveys and QuestionnairesTreatment OutcomeAnatomical and patient-reported prolapse outcomesApical prolapse surgeryEffectivenessRobotic-assisted sacral hysterocolpopexySafetyUphold™ vaginal mesh

Identifiers

PMID39776188
PMCPMC12003587

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.