Evidence map›Paper›PMID 39776028›Full record

ArticleInflammopharmacology2025

Olive oil and castor oil-based self-nanoemulsifying drug delivery system of flurbiprofen can relieve peripheral pain and inflammation through reduction of oxidative stress and inflammatory biomarkers: a comprehensive formulation and pharmacological insights.

Mazaghul Basar, Muhammad Imran Khan, Muhammad Furqan Akhtar, Fareeha Anwar, Ammara Saleem, Asadullah Madni, Zulcaif Ahmad, Ali Sharif, Bushra Akhtar, Uzma Shakoor and 1 more

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Article in Inflammopharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mazaghul BasarRiphah Institute of Pharmaceutical Sciences, Riphah International University, Lahore, 54000, Pakistan.
Muhammad Imran KhanRiphah Institute of Pharmaceutical Sciences, Riphah International University, Lahore, 54000, Pakistan. Imran.khan@riphah.edu.pk.ORCID http://orcid.org/0000-0002-6675-0491
Muhammad Furqan AkhtarRiphah Institute of Pharmaceutical Sciences, Riphah International University, Lahore, 54000, Pakistan.
Fareeha AnwarRiphah Institute of Pharmaceutical Sciences, Riphah International University, Lahore, 54000, Pakistan.
Ammara SaleemDepartment of Pharmacology, Faculty of Pharmaceutical Sciences, Government College University, Faisalabad, Pakistan.
Asadullah MadniDepartment of Pharmaceutics, Faculty of Pharmacy, The Islamia University of Bahawalpur, Bahawalpur, 63100, Pakistan.
Zulcaif AhmadRiphah Institute of Pharmaceutical Sciences, Riphah International University, Lahore, 54000, Pakistan.
Ali SharifInstitute of Pharmacy, Faculty of Pharmaceutical and Allied Health Sciences, Lahore College for Women University, Lahore, Pakistan.
Bushra AkhtarDepartment of Pharmacy, University of Agriculture, Faisalabad, Pakistan.
Uzma ShakoorIslam Medical and Pharmacy College, Gujranwala, Pakistan.
Aslam KhanRiphah Institute of Pharmaceutical Sciences, Riphah International University, Islamabad, 45210, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Flurbiprofen (FBP) is poorly water-soluble BCS class II drug with anti-inflammatory and analgesic effects, used to treat arthritis and degenerative joint diseases. This study was aimed to develop SNEDDS loaded with FBP. Six SNEDDS using two oils olive oil (F

Indexed as

Castor OilFlurbiprofenInflammationOlive OilOxidative StressPainAnalgesicsAnimalsAnti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalBiomarkersDrug Delivery SystemsEdemaEmulsionsMaleNanoparticlesAnalgesicsAnti-Inflammatory AgentsAnti-Inflammatory Agents, Non-SteroidalBiomarkersCastor OilEmulsionsFlurbiprofenOlive OilFlurbiprofenInflammatory biomarkersNon-steroidal anti-inflammatory drugOxidative stressPeripheral painSelf-nanoemulsifying drug delivery systemSolubility enhancement

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.