Evidence map›Paper›PMID 39775991›Full record

ReviewMolecular biology reports2025

LncRNA-miRNA-mRNA regulatory axes as potential biomarkers in cervical cancer: a comprehensive overview.

Dimple Patel, Sanu Thankachan, Saraswathy Sreeram, K P Kavitha, Shama Prasada Kabekkodu, Padmanaban S Suresh

Abstract readReview
PubMed Publisher
In one paragraph

Review in Molecular biology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Dimple Patel *National Resource Centre for Value Education in Engineering, Indian Institute of Technology, Delhi, Hauz Khas, New Delhi, 110016, India.
Sanu Thankachan *Department of Bioscience and Engineering, National Institute of Technology, Calicut, Kerala, 673601, India.
Saraswathy SreeramKasturba Medical College Mangalore, Manipal Academy of Higher Education, Manipal, Karnataka, India.
K P KavithaDepartment of Pathology, Aster Malabar Institute of Medical Sciences (MIMS), Calicut, Kerala, 673016, India.
Shama Prasada KabekkoduDepartment of Cell and Molecular Biology, Manipal School of Life Sciences, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.
Padmanaban S SureshDepartment of Bioscience and Engineering, National Institute of Technology, Calicut, Kerala, 673601, India. surepadman@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite the recent advances in vaccination and treatment strategies, cervical cancer continues to claim numerous lives every year. Owing to the fact that non-coding RNAs (ncRNAs) such as long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) interact with coding transcripts, and effectuate key roles in the tumorigenesis and metastasis of cervical cancer, there has been extensive research in recent years to explore their potential as biomarkers for early detection, or as therapeutic targets. Through this review, we aim to provide a comprehensive overview of the recent advancements in discoveries about cervical cancer-associated lncRNA-miRNA-mRNA axes, their dysregulation, and their roles in various signaling pathways associated with the growth, survival, invasion, and metastasis of cervical cancer cells. We further discuss the potential therapeutic strategies to utilize the dysregulated lncRNAs as diagnostic and prognostic biomarkers, and as therapeutic targets to ameliorate the prognosis of cervical cancer.

Indexed as

Biomarkers, TumorGene Expression Regulation, NeoplasticMicroRNAsRNA, Long NoncodingRNA, MessengerUterine Cervical NeoplasmsFemaleHumansPrognosisSignal TransductionBiomarkers, TumorMicroRNAsRNA, Long NoncodingRNA, MessengerBiomarkersCervical cancerlncRNAMetastasismiRNAmRNA

Identifiers

PMID39775991

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.