Evidence map›Paper›PMID 39775962›Full record

Trial reportSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025

The efficacy of lavender oil on fatigue and sleep quality in patients with hematological malignancy receiving chemotherapy: a single-blind randomized controlled trial.

Dilek Yildirim, Merve Harman Ozdogan, Seckin Erdal, Sevinc Selcuk, Azize Guneri, Elif Begum Simsek, Taha Berkay Can, Hazal Gunduz, Aysem Kuni

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05808296 (The Effect of Lavender Oil on Fatigue and Sleep Quality in Patients With Hematologic Malignancy), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05808296 naunknown statusnot on this map

The Effect of Lavender Oil on Fatigue and Sleep Quality in Patients With Hematologic Malignancy: A Single Blinding Randomized Controlled Study

TypeinterventionalSponsorIstanbul Aydın UniversityRan2022 to 2023Enrolled100ConditionsHematologic Malignancies, Patient ParticipationArmsLavander oil Aromatherapy, Saline Solution
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dilek YildirimDepartment of Nursing, Faculty of Health Sciences, Istanbul Aydin University, Florya Campus (Halit Aydın Campus) Inönü Street No: 38 Sefaköy - Kucukcekmece, Istanbul, Turkey. dilekyildirim@aydin.edu.tr.ORCID http://orcid.org/0000-0002-6228-0007
Merve Harman OzdoganDepartment of Medical Services and Techniques, Vocational School of Health Services, Sinop University, Sinop, Turkey.ORCID http://orcid.org/0000-0003-0408-0573
Seckin ErdalAdult Hematology Unit, Acibadem Altunizade Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-9279-9686
Sevinc SelcukAdult Hematology Unit, Acibadem Altunizade Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0001-6218-4405
Azize GuneriAdult Hematology Unit, Acibadem Altunizade Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-7681-1956
Elif Begum SimsekAdult Hematology Unit, Acibadem Altunizade Hospital, Istanbul, Turkey.ORCID http://orcid.org/0009-0005-9388-0223
Taha Berkay CanAdult Hematology Unit, Acibadem Altunizade Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0001-8013-7311
Hazal GunduzAdult Hematology Unit, Acibadem Altunizade Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0002-7952-6333
Aysem KuniAdult Hematology Unit, Acibadem Altunizade Hospital, Istanbul, Turkey.ORCID http://orcid.org/0000-0001-5102-2996

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study is to evaluate how aromatherapy with the inhalation of lavender oil affects fatigue and sleep quality in patients with hematological malignancies undergoing chemotherapy.

methodsThis randomized, parallel-group study was carried out in the Adult Bone Marrow Transplant unit and Hematology-Oncology clinics between January 2022 and April 2023. A total of 120 patients were assigned to experimental and control groups by randomization. The study was completed with 100 patients including 50 in the experimental group and 50 in the control group. Lavender essential oil was applied to the experimental group for 20 min prior to going to bed every night for 5 consecutive days. Physiological saline solution was applied to the control group in the same way. A Participant Information Form, the Richards-Campbell Sleep Questionnaire, and the Piper Fatigue Scale were used as data collection tools.

resultsThe experimental group showed a significantly higher sleep quality (p = 0.001) and had a significantly lower PFS scores (p = 0.001) compared to the control group. Also, the mean scores of the experimental group on the Behavioral, Sensory, and Cognitive subscales were statistically significantly lower than the scores of the control group (p < 0.05). Variables of lavender aromatherapy and total sleep quality accounted for 17.1% of the variance in fatigue levels (R

conclusionsConsequently, it was determined that aromatherapy with lavender essential oil significantly alleviated fatigue and lowered PFS total and subscale scores in patients with hematological malignancies undergoing chemotherapy. Also, sleep quality significantly enhanced in the overall PFS and its subscales.

trial registrationNCT05808296. Date of Registration: 30 March 2023.

Indexed as

AromatherapyFatigueHematologic NeoplasmsLavandulaOils, VolatilePlant OilsSleep QualityAdultAgedAntineoplastic AgentsFemaleHumansMaleMiddle AgedSingle-Blind MethodSurveys and QuestionnairesAntineoplastic Agentslavender oilOils, VolatilePlant OilsAromatherapyChemotherapyFatigueHematological malignanciesLavender oilSleep disordersSleep quality

Identifiers

PMID39775962
PMCPMC11711766

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.