ArticleOral radiology2025
A retrospective comparative fractal and radiomorphometric analysis of the effect of bisphosphonate use pattern and duration on the mandible.
Article in Oral radiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
5 citing papers in PubMed.
- Quantitative Bone Assessment in Medication-Related Osteonecrosis of the Jaw Using Fractal Analysis: A Systematic Review of the Literature and Clinical Perspectives.Dentistry journal · 2026Review
- Evaluation of the efficacy of clear aligners in mandibular advancement and their effect on mandibular trabecular structures using fractal dimension analysis.BMC oral health · 2025Article
- Investigation of the association between alterations in mandibular bone structure and serum bone metabolism biomarkers in male patients with chronic kidney disease: a retrospective cohort study.BMC oral health · 2025Article
- Jaw Bone Density in Chronic Areca Nut Chewers and Nonchewers Using Digital Panoramic Radiography Indices as a Screening Tool for Osteoporosis: Protocol for a Comparative Evaluation.JMIR research protocols · 2025Article
- Fractal Dimension Analysis of Mandibular Trabecular Bone in Patients Receiving Antiresorptive Therapy for Osteoporosis and Oncologic Conditions.Diagnostics (Basel, Switzerland) · 2025Article
Corrections and comments
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Authors and funding
2 authors.
Funding
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Abstract
aimsThe aim of this study was to investigate the effect of two different bisphosphonate types on bone using dental panoramic radiographs (DPRs) and to compare these findings with a healthy cohort. STUDY
designPanoramic dental radiographs of bisphosphonate users (30) and healthy individuals (30) were retrospectively evaluated for the study. Regarding FA, standardized 50 × 50 pixel regions of interest (ROI) were identified for each patient. Moreover, the assessment encompassed Mandibular Cortical Width (MCW), Panoramic Mandibular Index (PMI), and Mandibular Cortical Index (MCI). A significance level of p < 0.05 was deemed to be statistically significant.
resultsThe case group showed significantly higher MCW and PMI measurements than the control group (p < 0.001). Right and left MCI measurements differed depending on the type of drug used (p = 0.008 and p = 0.019, respectively). No discernible correlation was found between the time elapsed since the last dose and any measurement values (p > 0.05).
conclusionThis study showed that bisphosphonate type and duration of drug use have a significant effect on changes in cortical bone structure. The persistence of these effects, unaffected by the time since the previous dose, suggests that bisphosphonates have a long-lasting effect on bone.
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Registered trials
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