Evidence map›Paper›PMID 39775521›Full record

ArticlePloS one2025

Factors associated with the delay in diagnosis of extrapulmonary tuberculosis at the patient and health system level: A study from a rural setting in India.

Shoaib Hassan, Reza Yaesoubi, Ole Bjørgaas Helle Magnus, Mala Kanthali, Manju Raj Purohit, Tehmina Mustafa

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Shoaib HassanCentre for International Health, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.ORCID 0000-0002-4487-4020
Reza YaesoubiYale School of Public Health, Yale University, New Haven, Connecticut, United States of America.
Ole Bjørgaas Helle MagnusDepartment of Thoracic Medicine, Haukeland University Hospital, Bergen, Norway.
Mala KanthaliDepartment of Pathology, R.D. Gardi Medical College, Ujjain, India.
Manju Raj PurohitDepartment of Pathology, R.D. Gardi Medical College, Ujjain, India.
Tehmina MustafaCentre for International Health, Department of Global Public Health and Primary Care, University of Bergen, Bergen, Norway.ORCID 0000-0001-9822-1191

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWith the proportion of tuberculosis cases that are extrapulmonary tuberculosis (EPTB) increasing in recent years, understanding and addressing factors contributing to the prolonged time to diagnosis (TTD) of EPTB patients is vital.

methodsWe enrolled presumptive EPTB patients for a cohort study from 2018-2020 in Ujjain, India. Based on a structured questionnaire, the patients were interviewed for socio-demographic and clinical information, including previously visited health facilities (HF) for this illness. We analysed patients' TTD, healthcare access, and referral pathways.

findingsEPTB (54%) and non-TB (58%) patients visited dispensaries during their first visit to a formal HF. Patients visited multiple HFs, including dispensaries (54%) and regional hospitals (32%), during 1-4 visits but did not receive an appropriate diagnosis. Less than 2% of the patients accessed private HFs. Most of the adult EPTB (83%) and non-TB (76%) patients were self-referred to our study site, where they were diagnosed. Our statistical models highlighted low-middle income groups, longer distances and longer travel time to HFs, and potentially less-empowered occupations as housewives with a prolonged TTD. Patients with a longer wait, including travel time, had a shorter TTD.

conclusionWe found individual, societal-level, and structural barriers to healthcare access and utilisation and their association with diagnostic delay among adult and paediatric EPTB patients.

Indexed as

Delayed DiagnosisRural PopulationTuberculosisAdolescentAdultChildChild, PreschoolCohort StudiesFemaleHealth Services AccessibilityHumansIndiaMaleMiddle AgedSurveys and QuestionnairesTuberculosis, Extrapulmonary

Identifiers

PMID39775521
PMCPMC11706485

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.