Evidence map›Paper›PMID 39775456›Full record

ArticleApplied biochemistry and biotechnology2025

Co-encapsulation of Creatininase, Creatinase, and Sarcosine Oxidase in Yeast Spore for Creatinine Degradation.

Jun Kong, XiaoLong Han, HuaPing Pan, MeiLing Lei, ShuQi Qi

Abstract read
PubMed Publisher
In one paragraph

Article in Applied biochemistry and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jun KongSchool of Life Science and Bioengineering, Jining University, 1 Xingtan Road, Qufu, 273155, Shangdong, China. 369735491@qq.com.ORCID http://orcid.org/0009-0005-6595-8804
XiaoLong HanSchool of Life Science and Bioengineering, Jining University, 1 Xingtan Road, Qufu, 273155, Shangdong, China.
HuaPing PanSchool of Pharmacy, Jiangxi University of Chinese Medicine, 1688 Meiling Road, Nanchang, 330004, Jiangxi, China.
MeiLing LeiSchool of Life Science and Bioengineering, Jining University, 1 Xingtan Road, Qufu, 273155, Shangdong, China.
ShuQi QiSchool of Life Science and Bioengineering, Jining University, 1 Xingtan Road, Qufu, 273155, Shangdong, China.

Funding

Natural Science Foundation of Shandong Province ZR2020MC017
6 · The paper itself

Abstract

Creatinine clearance is used to reflect the glomerular filtration rate to assess kidney function. Creatinine degradation-related enzymes have been used for creatinine detection in clinical medicine. The mixture of spores encapsulating either creatininase or creatinase or sarcosine oxidase could mediate a three-step reaction to produce hydrogen peroxide from creatinine. In this study, to achieve consecutive and efficient creatinine detection, degradation enzymes creatininase, creatinase, and sarcosine oxidase were co-encapsulated in a single Saccharomyces cerevisiae spore. The co-encapsulation spores performed high specific activity and enzymatic properties and converted creatinine to H

Indexed as

AmidohydrolasesCreatinineSaccharomyces cerevisiaeSarcosine OxidaseSpores, FungalUreohydrolasesHydrogen PeroxideAmidohydrolasescreatinasecreatininaseCreatinineHydrogen PeroxideSarcosine OxidaseUreohydrolasesCo-encapsulationCreatinine degradationSaccharomyces cerevisiaeSpores

Identifiers

PMID39775456

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.