Evidence map›Paper›PMID 39775123›Full record

SynthesisNeurosurgical review2025

Leveraging machine learning algorithms to forecast delayed cerebral ischemia following subarachnoid hemorrhage: a systematic review and meta-analysis of 5,115 participants.

Ibrahim Mohammadzadeh, Behnaz Niroomand, Pooya Eini, Homayoon Khaledian, Tannaz Choubineh, Sabino Luzzi

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Neurosurgical review, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 11 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 11 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 11 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ibrahim MohammadzadehDepartment of Skull Base Research Center, Loghman-Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Ibrahim.mdz7777@gmail.com.ORCID http://orcid.org/0000-0002-8862-0778
Behnaz NiroomandDepartment of Skull Base Research Center, Loghman-Hakim Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0001-5184-7445
Pooya EiniToxicological Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.ORCID http://orcid.org/0000-0002-9457-8588
Homayoon KhaledianSina Trauma and Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Tannaz ChoubinehDepartment of Computer (Computer Engineering), North Tehran Branch, Islamic Azad University, Tehran, Iran.ORCID http://orcid.org/0009-0008-2384-4640
Sabino LuzziDepartment of Medicine, Surgery, and Pharmacy University of Sassari, Sassari, SD, Italy.ORCID http://orcid.org/0000-0002-1381-8528

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

It is feasible to predict delayed cerebral ischemia (DCI) after aneurysmal subarachnoid hemorrhage (aSAH) using Artificial intelligence (AI) algorithms, which may offer significant improvements in early diagnosis and patient management. This systematic review and meta-analysis evaluate the efficacy of machine learning (ML) in predicting DCI, aiming to integrate complex clinical data to enhance diagnostic accuracy. We searched PubMed, Scopus, Web of science, and Embase databases without restrictions until June 2024, applying PRISMA guidelines. Out of 1498 studies screened, 10 met our eligibility criteria involving ML approaches in patients with confirmed aSAH. The studies employed various ML algorithms and reported differential ML metrics outcomes. Meta-analysis was performed on eight studies, which resulted in a pooled sensitivity of 0.79 [95% CI: 0.63-0.89], specificity of 0.78[95% CI: 0.68-0.85], positive DLR of 3.54 [95% CI: 2.22-5.64] and the negative DLR of 0.28 [95% CI: 0.15-0.52], diagnostic odds ratio of 12.82 [95% CI: 4.66-35.28], the diagnostic score of 2.55 [95% CI: 1.54-3.56], and the area under the curve (AUC) of 0.85. These findings show significant diagnostic accuracy and demonstrate the potential of ML algorithms to significantly improve the predictability of DCI, implying that ML could impart a significant role on improving clinical decision making. However, variability in methodological approaches across studies shows a need for standardization to realize the full benefits of ML in clinical settings.

Indexed as

Brain IschemiaMachine LearningSubarachnoid HemorrhageHumansCerebral ischemiaDiagnostic accuracyMachine learningMeta-analysisPredictive modelingPrognosisSubarachnoid hemorrhage

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.