Evidence map›Paper›PMID 39775062›Full record

ArticleArchives of dermatological research2025

Negative association between the neutrophil percentage-to-albumin ratio (NPAR) and psoriasis: a retrospective cross-sectional study.

Junjie Zhang, Dongzhe Li, Hongpeng Guo, Jie Yang, He Zhang, Jingdong Wu, Xiao Sun

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Article in Archives of dermatological research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Junjie ZhangLiaoning University of Traditional Chinese Medicine, Liaoning, 110847, Shenyang, China.
Dongzhe LiDepartment of General Surgery, Central Hospital Affiliated to Shenyang Medical College, Liaoning, 110024, Shenyang, China.
Hongpeng GuoDepartment of General Surgery, Central Hospital Affiliated to Shenyang Medical College, Liaoning, 110024, Shenyang, China.
Jie YangLiaoning University of Traditional Chinese Medicine, Liaoning, 110847, Shenyang, China.
He ZhangSports Medicine, Tongliao People's Hospital, Tongliao, 028000, Inner Mongolia, China.
Jingdong WuLiaoning University of Traditional Chinese Medicine, Liaoning, 110847, Shenyang, China. Lnzywjd0719@163.com.
Xiao SunDepartment of Pathology, Central Hospital Affiliated to Shenyang Medical College, No.5 Nanqi West Road, Liaoning, 110024, Shenyang, China. 799431470@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Among patients with psoriasis, there was not much research regarding the assessment of neutrophil percentage-to-albumin ratio (NPAR) in patients with psoriasis. This cross-sectional study aimed to investigate the association between NPAR and prevalence of psoriasis in US adults. Data from adults aged 20 to 80 years in the National Health and Nutrition Examination Survey (NHANES) from 2003 to 2006 and 2009 to 2014 was utilized. Institutional Review Board approval and documented written consent was obtained from participants by NHANES (Protocol #2005-06). Differences between the groups were further explored. The univariate, multivariate logistic regressions and restricted cubic splines (RCS) regression were used to investigate the correlation between NPAR and psoriasis, with results expressed as odds ratios (OR) and 95% confidence intervals (CI). Subgroup analysis of the associations between NPAR and psoriasis was carried out to investigate if the impact of the NPAR varied among different subgroups. Of the 17,489 adults included in the study, 500 (2.9%) were diagnosed with psoriasis. NPAR (per 10 unit) was negatively associated with prevalence of psoriasis (β = 0.55, 95% CI 0.37, 0.82), after being fully adjusted. A non-linear was observed in the dose-response relationship between NPAR and prevalence of psoriasis (P for non-linearity 0.021). In the subgroup analysis, effect size of NPAR on the presence of psoriasis in subgroups was stable (all P values > 0.05). There exists a stable and strong negative non-linearly association between NPAR and prevalence of psoriasis. The potential role and value in the clinical diagnosis and prognostic assessment of the NPAR in psoriasis calls for further longitudinal studies.

Indexed as

NeutrophilsNutrition SurveysPsoriasisAdultAgedAged, 80 and overCross-Sectional StudiesFemaleHumansLeukocyte CountMaleMiddle AgedPrevalenceRetrospective StudiesSerum AlbuminUnited StatesSerum AlbuminCross-sectional studyNeutrophil-percentage-to-albumin ratio (NPAR)NHANESPsoriasisUS adults

Identifiers

PMID39775062

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.