Evidence map›Paper›PMID 39774864›Full record

ArticleIntensive care medicine2025

Utilization and outcomes of life-supporting interventions in older ICU patients in Japan: a nationwide registry study.

Junji Shiotsuka, Tomoyuki Masuyama, Shigehiko Uchino, Yusuke Sasabuchi, Reina Suzuki, Shohei Ono, Koichi Yoshinaga, Yusuke Iizuka, Masamitsu Sanui

Abstract read
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Article in Intensive care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  3. Observational
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  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Junji ShiotsukaDepartment of Anesthesiology and Critical Care Medicine, Jichi Medical University, Tochigi, Japan.ORCID 0000-0001-9368-0591
Tomoyuki MasuyamaDepartment of Emergency and Critical Care Medicine, Dokkyo Medical University, Tochigi, Japan. tomomasuyama@gmail.com.ORCID 0000-0003-2148-5556
Shigehiko UchinoDepartment of Anesthesiology and Critical Care Medicine, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Yusuke SasabuchiDepartment of Real-World Evidence, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan.
Reina SuzukiDepartment of General Internal Medicine, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Shohei OnoDepartment of Anesthesiology and Critical Care Medicine, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Koichi YoshinagaDepartment of Anesthesiology and Critical Care Medicine, Jichi Medical University, Tochigi, Japan.
Yusuke IizukaDepartment of Anesthesiology and Critical Care Medicine, Saitama Medical Center, Jichi Medical University, Saitama, Japan.
Masamitsu SanuiDepartment of Anesthesiology and Critical Care Medicine, Jichi Medical University, Tochigi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study is to describe the implementation of life-supporting interventions and the short-term outcomes of older patients in ICUs in Japan.

methodsAll adult patients admitted to ICUs participating in the Japanese Intensive Care Patient Database (JIPAD) from April 1, 2015, to March 31, 2022, were eligible for inclusion. Information, including life-supporting interventions, was retrieved from the database. Patients were divided into six age groups. The primary outcome of interest was the proportion of receiving a composite of the following interventions: mechanical ventilation, continuous renal replacement therapy, and veno-venous or veno-arterial extracorporeal membrane oxygenation.

resultsData of a total of 233,093 patients were analyzed. The median age was 71 years, with 18.2% of the patients in their 80s, 5303 patients in their 90s (2.3%), and 67 patients in their 100s. Many life-supporting interventions were provided to older patients. The proportion of patients older than 90 years who received the composite interventions decreased from 40.4% in 18-59 to 27.6% in 90-99. Non-invasive ventilation (NIV) use increased with age, resulting in a consistent proportion of patients receiving either NIV or mechanical ventilation until their 90s. ICU mortality for patients aged 80 years or older was 5.6%, and hospital mortality for this age group was 12.9%. Approximately half of the patients in their 80s and 60% of those older than 90 years did not return home.

conclusionAlthough life-supporting interventions tended to decrease with age, a considerable number of patients of advanced age still received these interventions.

Indexed as

Intensive Care UnitsLife Support CareAdultAgedAged, 80 and overAge FactorsExtracorporeal Membrane OxygenationFemaleHospital MortalityHumansJapanMaleMiddle AgedRegistriesRenal Replacement TherapyRespiration, ArtificialIntensive care unitsLife-supporting interventionsOlder patientsResource utilizationTreatment limitation

Identifiers

PMID39774864

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.