Evidence map›Paper›PMID 39774675›Full record

ReviewJournal of pediatric psychology2025

Topical review: sleep regulation as a novel target for treating preschool-aged children with attention-deficit/hyperactivity disorder symptoms.

Jessica R Lunsford-Avery, Jade Q Wu, Alexis French, Naomi O Davis

Abstract readReview
In one paragraph

Review in Journal of pediatric psychology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jessica R Lunsford-AveryDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, United States.ORCID 0000-0003-0264-6991
Jade Q WuBehavioral Sleep Medicine Program, Durham VA Medical Center, Durham, NC, United States.
Alexis FrenchDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, United States.
Naomi O DavisDepartment of Psychiatry and Behavioral Sciences, Duke University School of Medicine, Durham, NC, United States.

Funding

Sleep Dysfunction and Neurocognitive Outcomes in Adolescent ADHDK23MH108704 · NIMH · DUKE UNIVERSITY · PI LUNSFORD-AVERY, JESSICA RUTH · 2016 to 2022
$837k
Sustainable Habits for Encouraging Even Teen Sleep (SHEETS): A Digital Intervention to Enhance Sleep Regularity and Psychiatric Health in AdolescentsR34MH128440 · NIMH · DUKE UNIVERSITY · PI DUKE, NAOMI N, LUNSFORD-AVERY, JESSICA RUTH · 2022 to 2024
$725k
Preschool Attention and Sleep Support (PASS): A Telehealth Intervention for Children at Risk for ADHDR34MH131994 · NIMH · DUKE UNIVERSITY · PI LUNSFORD-AVERY, JESSICA RUTH · 2023 to 2025
$688k
NIMH NIH HHS K23 MH108704NIMH NIH HHS R34 MH128440NIMH NIH HHS R34 MH131994NIMH NIH HHS R34-MH-131994
6 · The paper itself

Abstract

objectiveElevated attention-deficit/hyperactivity disorder (ADHD) symptoms in preschoolers are a risk factor for poorer psychiatric health, cognitive deficits, and social and academic impairment across the lifespan. The first-line treatment for these preschoolers, behavioral parent training (BPT), reduces children's disruptive behaviors and parenting stress, yet its impact on core ADHD symptoms is inconsistent. Early interventions targeting biological mechanisms linked to core ADHD pathophysiology are critically needed.

methodsThis topical review explores sleep dysregulation as a potential key target for early intervention for ADHD symptoms among preschoolers.

resultsSleep dysregulation is common in school-aged children with ADHD, and treating sleep improves core ADHD symptoms in older children. Cross-sectional and prospective research with preschoolers offers compelling evidence that sleep dysregulation and ADHD symptoms are closely linked over the course of early development. BPT and behavioral sleep medicine (BSM) interventions share an underlying theoretical framework and could be streamlined to target sleep in addition to daytime behaviors.

conclusionsNovel early interventions targeting underlying biological mechanisms linked to core ADHD pathophysiology are critically needed to improve the trajectories of ADHD symptoms, comorbidity, and functional deficits for preschoolers with elevated ADHD symptoms. Sleep regulation is a promising mechanistic treatment target for this population, and future interventions may draw from the shared behavioral principles of BPT and BSM to target behaviors across the 24-hr period and employ scalable formats to optimize the number of families who can benefit from parent-based interventions targeting ADHD symptoms and sleep in early development.

Indexed as

Attention Deficit Disorder with HyperactivityBehavior TherapySleep Wake DisordersChild, PreschoolHumansADHDearly developmentearly interventionpreschoolsleep

Identifiers

PMID39774675
PMCPMC11981054

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.