Evidence map›Paper›PMID 39774532›Full record

ArticlePloS one2025

Global, regional, and national survey on burden and Quality of Care Index (QCI) of orofacial clefts: Global burden of disease systematic analysis 1990-2019.

Ahmad Sofi-Mahmudi, Erfan Shamsoddin, Sahar Khademioore, Yeganeh Khazaei, Amin Vahdati, Marcos Roberto Tovani-Palone

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Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Ahmad Sofi-MahmudiNational Pain Centre, Department of Anesthesia, McMaster University, Hamilton, ON, Canada.ORCID 0000-0001-6829-0823
Erfan ShamsoddinCochrane Iran Associate Centre, National Institute for Medical Research Development (NIMAD), Tehran, Iran.
Sahar KhademiooreDepartment of Health Research Methods, Evidence and Impact, McMaster University, Hamilton, ON, Canada.
Yeganeh KhazaeiDepartment of Statistics, Statistical Consultation Unit, StaBLab, LMU Munich, Munich, Germany.
Amin VahdatiCentre for Biostatistics, University of Manchester, Manchester, United Kingdom.
Marcos Roberto Tovani-PaloneRibeirão Preto Medical School, University of São Paulo, São Paulo, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOrofacial clefts are the most common craniofacial anomalies that include a variety of conditions affecting the lips and oral cavity. They remain a significant global public health challenge. Despite this, the quality of care for orofacial clefts has not been investigated at global and country levels.

objectiveWe aimed to measure the quality-of-care index (QCI) for orofacial clefts worldwide.

methodsWe used the 2019 Global Burden of Disease data to create a multifactorial index (QCI) to assess orofacial clefts globally and nationally. By utilizing data on incidence, prevalence, years of life lost, and years lived with disability, we defined four ratios to indirectly reflect the quality of healthcare. Subsequently, we conducted a principal component analysis to identify the most critical variables that could account for the observed variability. The outcome of this analysis was defined as the QCI for orofacial clefts. Following this, we tracked the QCI trends among males and females worldwide across various regions and countries, considering factors such as the socio-demographic index and World Bank classifications.

resultsGlobally, the QCI for orofacial clefts exhibited a consistent upward trend from 1990 to 2019 (66.4 to 90.2) overall and for females (82.9 to 94.3) and males (72.8 to 93.6). In the year 2019, the top five countries with the highest QCI scores were as follows: Norway (QCI = 99.9), Ireland (99.4), France (99.4), Germany (99.3), the Netherlands (99.3), and Malta (99.3). Conversely, the five countries with the lowest QCI scores on a global scale in 2019 were Somalia (59.1), Niger (67.6), Burkina Faso (72.6), Ethiopia (73.0), and Mali (74.4). Gender difference showed a converging trend from 1990 to 2019 (optimal gender disparity ratio (GDR): 123 vs. 163 countries), and the GDR showed a move toward optimization (between 0.95 and 1.05) in the better and worse parts of the world.

conclusionDespite the positive results regarding the QCI for orofacial clefts worldwide, some countries showed a slight negative trend.

Indexed as

Cleft LipCleft PalateGlobal Burden of DiseaseQuality of Health CareFemaleGlobal HealthHumansIncidenceMalePrevalenceSurveys and Questionnaires

Identifiers

PMID39774532
PMCPMC11709310

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.