Evidence map›Paper›PMID 39773836›Full record

ArticleBritish journal of sports medicine2025

Association between recorded physical activity and cancer progression or mortality in individuals diagnosed with cancer in South Africa.

Ntokozo Mabena, Nivash Rugbeer, Sandra Lehmann, Georgia Torres, Deepak Patel, Mosima Mabunda, Mike Greyling, Jane S Thornton, Yun-Hee Choi, Saverio Stranges and 1 more

Abstract read
In one paragraph

Article in British journal of sports medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ntokozo Mabena *Discovery Vitality, Sandton, South Africa.
Nivash Rugbeer *Physiology, Division of Biokinetics and Sports Science, University of Pretoria, Pretoria, South Africa.ORCID http://orcid.org/0000-0003-4437-7240
Sandra LehmannDiscovery Vitality, Sandton, South Africa.
Georgia TorresCentre for Exercise Science and Sports Medicine, University of Witwatersrand, Johannesburg, South Africa.ORCID http://orcid.org/0000-0002-0197-4718
Deepak PatelDiscovery Vitality, Sandton, South Africa.
Mosima MabundaDiscovery Vitality, Sandton, South Africa.
Mike GreylingData Management and Statistical Analysis (DMSA), Johannesburg, South Africa.
Jane S ThorntonPublic Health and Family Medicine, University of Western Ontario Schulich School of Medicine and Dentistry, London, Ontario, Canada.ORCID http://orcid.org/0000-0002-3519-7101
Yun-Hee ChoiEpidemiology and Biostatistics, University of Western Ontario Faculty of Health Sciences, London, Ontario, Canada.
Saverio StrangesDepartment of Family Medicine, Western University Faculty of Health Sciences, London, Ontario, Canada.
Jon S PatriciosWits Sport and Health (WiSH), School of Clinical Medicine, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa jpat@mweb.co.za.ORCID http://orcid.org/0000-0002-6829-4098

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aimed to determine the association between progression and mortality in individuals with stage 1 cancer and their recorded physical activity before the diagnosis of the cancer.

methodsWe included 28 248 members with stage 1 cancers enrolled in an oncology programme in South Africa. Physical activity was recorded using fitness devices, logged gym sessions and participation in organised fitness events. Levels of physical activity over the 12 months before cancer diagnosis were categorised as no physical activity, low physical activity (an average of <60 min/week) and moderate to high physical activity (≥60 min/week). Measured outcomes were time to progression, time to death and all cause mortality.

resultsPhysically active members showed lower rates of cancer progression and lower rates of death from all causes. The HR for progression to higher stages or death was 0.84 (95% CI 0.79 to 0.89), comparing low activity with no physical activity, and 0.73 (95% CI 0.70 to 0.77), comparing medium to high physical activity with no physical activity. The HR for all cause mortality was 0.67 (95% CI 0.61 to 0.74), comparing low physical activity with no activity, and 0.53 (95% CI 0.50 to 0.58), comparing medium to high physical activity with no physical activity.

conclusionsIndividuals engaging in any level of recorded physical activity showed a reduced risk of cancer progression or mortality than those not physically active. There was a further reduction among individuals with moderate to high levels of physical activity compared with those with lower levels.

Indexed as

ExerciseNeoplasmsAdultAgedDisease ProgressionFemaleHumansMaleMiddle AgedSouth AfricaDeathPhysical activity

Identifiers

PMID39773836
PMCPMC12171519

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.