Evidence map›Paper›PMID 39773670›Full record

ArticleBMC research notes2025

The prognosis for delayed immune recovery in HIV-infected children might be associated with pre-cART CD4

Funsho J Ogunshola, Ruhul A Khan, Musie Ghebremichael

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC research notes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

Funsho J OgunsholaRagon Institute of MGH, MIT, and Harvard, 600 Main Street, Cambridge, MA, 02139, USA.
Ruhul A KhanDepartment of Mathematics, University of Arizona, 617 N. Santa Rita Ave., Tucson, AZ, 85721, USA.
Musie GhebremichaelRagon Institute of MGH, MIT, and Harvard, 600 Main Street, Cambridge, MA, 02139, USA. musie_ghebremichael@dfci.harvard.edu.

Funding

The impact of HIV viral diversity and cellular immunity on HIV pathogenesisP30AI060354 · NIAID · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI RAJESH T GANDHI · 2004 to 2026
$94.4M
NIAID NIH HHS P30 AI060354NIH/NAIDS P30-AI 060354
6 · The paper itself

Abstract

backgroundImmune reconstitution following the initiation of combination antiretroviral therapy (cART) significantly impacts the prognosis of individuals infected with human immunodeficiency virus (HIV). Our previous studies have indicated that the baseline CD4

resultsWe confirmed that the baseline CD4

Indexed as

CoinfectionHIV InfectionsTuberculosisAdolescentAnti-HIV AgentsCD4 Lymphocyte CountCD4-Positive T-LymphocytesChildChild, PreschoolFemaleFollow-Up StudiesHumansImmune ReconstitutionInfantInfant, NewbornMaleAnti-HIV AgentsCART initiationCD4+ T cell countHIVImmune recoveryPiecewise linear and mixed-effects modelsTB

Identifiers

PMID39773670
PMCPMC11707843

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.