Evidence map›Paper›PMID 39773486›Full record

ArticleBMC veterinary research2025

Validation of a method for estimating pulmonary dead space in ventilated beagles to correct exhaled propofol concentration in mixed air.

Xiaoxiao Li, Pan Chang, Xing Liu, Zhongjun Zhao, Yixiang Duan, Wensheng Zhang

Abstract readValidation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC veterinary research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaoxiao Li *Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, China.
Pan Chang *Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, China.
Xing LiuDepartment of Anesthesiology, West China Hospital, Sichuan University, Chengdu, China.
Zhongjun ZhaoSchool of Mechanical Engineering, Sichuan University, Chengdu, China.
Yixiang DuanSchool of Mechanical Engineering, Sichuan University, Chengdu, China.
Wensheng ZhangDepartment of Anesthesiology, West China Hospital, Sichuan University, Chengdu, China. zhang_ws@scu.edu.cn.

Funding

National Natural Science Foundation of China 82304648Science Fund for Distinguished Young Scholars of Sichuan Province 2023NSFSC1677
6 · The paper itself

Abstract

backgroundMixed exhaled air has been widely used to determine exhaled propofol concentrations with online analyzers, but changes in dead space proportions may lead to inaccurate assessments of critical drug concentration data. This study proposes a method to correct propofol concentration in mixed air by estimating pulmonary dead space through reconstructing volumetric capnography (Vcap) from time-CO

methodsExisting monitoring parameters, including time-volume and time-CO

resultsAfter 30 min of continuous propofol administration, a stable respiratory cycle was selected for analysis in each beagle. The calculated V

conclusionThe physiological dead space to tidal volume ratio from mixed air in beagles can be accurately measured using the existing time-volume and time-CO

Indexed as

Anesthetics, IntravenousPropofolRespiratory Dead SpaceTidal VolumeAnimalsBreath TestsCapnographyCarbon DioxideDogsExhalationFemaleMaleMass SpectrometryRespiration, ArtificialAnesthetics, IntravenousCarbon DioxidePropofolDead spaceOnline analysisPropofolVacuum ultraviolet time-of-flight mass spectrometryVolumetric capnography

Identifiers

PMID39773486
PMCPMC11706130

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.