ArticleBMC women's health2025
Global, regional, and national burden of anxiety disorders during the perimenopause (1990-2021) and projections to 2035.
Article in BMC women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.
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Who cites it
8 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Experience of menopause across ethnic groups: mapping the evidence through a scoping review.Frontiers in reproductive health · 2025Pooled it
- Effects of resveratrol on postmenopausal women: a systematic review and meta-analysis.Frontiers in pharmacology · 2025Pooled it
- A perspective on economic barriers and disparities in access to hormone replacement therapy in LMICs (MARIE-WP2b).Scientific reports · 2026Article
- Biopsychosocial determinants of anxiety and depression among working mothers in China: A public mental health perspective.Narra J · 2025Article
- The correlation of vaginal flora and anxiety in perimenopause women: a prospective study.BMC women's health · 2025Article
- Effect of curcumin on fatigue and musculoskeletal health in postmenopausal women: a double-blind randomised controlled trial.BMJ open · 2025Article
- Inner strengths as buffers against the impact of insecure attachment on depressive symptoms in working women.Frontiers in public health · 2025Article
- Burden and trend of cardiovascular diseases in youths aged 0-19 years in China, Asia, and the world, with forecasts to 2036: a systematic analysis of the global burden of disease study 2021.Frontiers in public health · 2025Article
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5 authors.
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Abstract
purposePerimenopause is associated with an increased risk of anxiety disorders, largely due to hormonal changes affecting the body's regulatory feedback mechanisms. This study aims to provide a comprehensive analysis of the global burden of anxiety disorders among perimenopausal women.
methodsData from the 2021 Global Burden of Disease (GBD) database were utilized to assess disability-adjusted life years associated with anxiety disorders linked to perimenopause. We calculated trends using the estimated average percent change, and future projections were made using the Bayesian age-period-cohort model to estimate disability-adjusted life year trends for anxiety disorders from 2022 to 2035.
resultsBetween 1990 and 2021, the global age-standardized disability-adjusted life year rate for anxiety disorders among perimenopausal women increased from 625.51 (95% uncertainty interval: 429.1-891.09) to 677.15 (95% uncertainty interval: 469.45-952.72), indicating a rising trend with an estimated average percent change of 0.081 (95% confidence interval: 0.0043-0.143). Regional differences were noted, with anxiety disorder burdens varying across areas with different sociodemographic index levels. Projections suggest that by 2035, the global burden of anxiety disorders in perimenopausal women will rise to 1,180.43 per 100,000, a 40.67% increase compared with 2021 levels.
conclusionThe burden of anxiety disorders during perimenopause is a growing global concern, with a significant increase anticipated in the coming years. Targeted prevention and intervention strategies are urgently needed to mitigate this rising burden and improve mental health outcomes during perimenopause.
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