Evidence map›Paper›PMID 39773438›Full record

ArticleBMC endocrine disorders2025

Change in pericardial fat volume in postmenopausal women with papillary thyroid cancer undergoing thyrotropin suppressive therapy.

Yunkyung Jeon, Doohwa Kim, Mijin Kim, Bo Hyun Kim, Kyoungjune Pak, Jihyun Kim, Keunyoung Kim

Abstract read
In one paragraph

Article in BMC endocrine disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yunkyung JeonDivision of Endocrinology, Department of Internal Medicine, Pusan National University Hospital, Busan, Republic of Korea.
Doohwa KimDivision of Endocrinology, Department of Internal Medicine, Pusan National University Hospital, Busan, Republic of Korea.
Mijin KimDivision of Endocrinology, Department of Internal Medicine, Pusan National University Hospital, Busan, Republic of Korea.
Bo Hyun KimDivision of Endocrinology, Department of Internal Medicine, Pusan National University Hospital, Busan, Republic of Korea.
Kyoungjune PakDepartment of Nuclear Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Republic of Korea.
Jihyun KimDepartment of Nuclear Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Republic of Korea.
Keunyoung KimDepartment of Nuclear Medicine and Biomedical Research Institute, Pusan National University Hospital, Busan, Republic of Korea. nmpnuh@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite TSH suppressive therapy improve the prognosis for the patient with differentiated thyroid cancer (DTC), there is an increasing concern regarding the potentially harmful effects of lifelong TSH suppression. Therefore, we aimed to examine the changes in body composition under TSH suppression in postmenopausal women with DTC.

methodsThe body composition was assessed by the volumes as following; fat tissues of the epicardium and abdominal visceral and subcutaneous areas; bilateral psoas muscle or thigh muscle. Each volumetric measurements were performed using computed tomography (CT) scans using baseline and follow-up fluorine-18 fluorodeoxyglucose positron emission tomography/CT (

resultsThe 43 patients' median age was 50.0 years, and median body mass index (BMI) was 23.53 (interquartile range[IQR]: 22.19- 24.92) at the initial

conclusionBoth skeletal muscle and abdominal fat volumes did not change, whereas epicardial fat volume increased over less than 2 years of observation under TSH suppressive therapy. Further research is needed for the harmonization of benefits or losses with the optimal TSH concentration in postmenopausal women.

Indexed as

PericardiumPositron Emission Tomography Computed TomographyPostmenopauseThyroid NeoplasmsThyrotropinAdipose TissueAdultBody CompositionFemaleFluorodeoxyglucose F18Follow-Up StudiesHumansMiddle AgedPrognosisRepublic of KoreaThyroid Cancer, PapillaryFluorodeoxyglucose F18ThyrotropinBody compositionDifferentiated thyroid cancerEpicardial fatF-18 FDG PET/CTMenopauseTSH suppressive therapy

Identifiers

PMID39773438
PMCPMC11707903

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.