Trial reportJournal of orthopaedic surgery and research2025
Effect of knee extension constraint training on walking biomechanics 6 months after anterior cruciate ligament reconstruction: a double-blind randomized controlled clinical trial.
Trial report in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Correlation Between Functional Scores and Objective Gait Parameters Following Rotating Hinge Knee Megaprosthesis Reconstruction.Orthopaedic surgery · 2026Article
- Advances in Gait Alterations and Rehabilitation After Anterior Cruciate Ligament Reconstruction: Biomechanics and Emerging Technologies.Orthopaedic surgery · 2026Review
- Study on the Influence of Protector Design on the Biomechanical Characteristics of Knee Joint Movement.Sensors (Basel, Switzerland) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundThe incidence of knee osteoarthritis after anterior cruciate ligament reconstruction (ACLR) is high to 57%, and the biomechanical abnormality during walking is one of the reasons. The purpose of this study was to investigate the effect of 12 weeks of knee extension constraint training on walking biomechanics during the stance phase of injured side after ACLR.
methodsForty-five patients were randomly assigned to three groups based on different brace conditions from 13 weeks to 24 weeks after ACLR: experimental (brace with knee extension constraint), placebo (brace without knee extension constraint), and control (no brace). Gait analysis was performed 3 and 6 months after ACLR. The peak for knee flexion angle (KFA), knee extension moment (KEM), and vertical ground reaction force (vGRF) were compared by 2 (time) x 3 (group) repeated-measures analysis of covariance (ANCOVA), and pairwise comparisons were conducted. .
resultsThere was a significant time x group interaction for the peak KFA (p = 0.047), and there was no significant time x group interaction for the peak KEM and peak vGRF. The pairwise comparisons showed that there were no statistical differences among the groups both the pre-intervention and post-intervention in the peak KFA, peak KEM, and peak vGRF. Compared with pre-intervention, the peak vGRF in the experimental group was significantly greater (p = 0.009) and the peak KFA in the control group was significantly lower (p = 0.041) post-intervention. There were not significantly different in the placebo group between pre-intervention and post-intervention.
conclusion12 weeks of knee extension constraint training can increase lower extremity loading on the injured side, may be a potential therapeutic adjunct to improve abnormal gait after ACLR.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.