Evidence map›Paper›PMID 39772968›Full record

ReviewmSystems2025

Cooling perspectives on the risk of pathogenic viruses from thawing permafrost.

Rachel Mackelprang, Robyn A Barbato, Andrew M Ramey, Ursel M E Schütte, Mark P Waldrop

Abstract readReview
In one paragraph

Review in mSystems, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rachel MackelprangCalifornia State University Northridge, Northridge, California, USA.ORCID 0000-0002-7213-7415
Robyn A BarbatoU.S. Army Cold Regions Research and Engineering Laboratory, Hanover, New Hampshire, USA.ORCID 0000-0001-8314-8526
Andrew M RameyU.S. Geological Survey Alaska Science Center, Anchorage, Alaska, USA.ORCID 0000-0002-3601-8400
Ursel M E SchütteInstitute of Arctic Biology, University of Alaska Fairbanks, Fairbanks, Alaska, USA.ORCID 0000-0002-7201-786X
Mark P WaldropU.S. Geological Survey, Geology, Minerals, Energy, and Geophysics Science Center, Moffett Field, Moffett Field, California, USA.ORCID 0000-0003-1829-7140

Funding

DOI | U.S. Geological Survey (USGS)National Science Foundation (NSF) DEB 2029573U.S. Department of Defense (DOD) Army Program Element PE 0602144A
6 · The paper itself

Abstract

Climate change is inducing wide-scale permafrost thaw in the Arctic and subarctic, triggering concerns that long-dormant pathogens could reemerge from the thawing ground and initiate epidemics or pandemics. Viruses, as opposed to bacterial pathogens, garner particular interest because outbreaks cannot be controlled with antibiotics, though the effects can be mitigated by vaccines and newer antiviral drugs. To evaluate the potential hazards posed by viral pathogens emerging from thawing permafrost, we review information from a diverse range of disciplines. This includes efforts to recover infectious virus from human remains, studies on disease occurrence in polar animal populations, investigations into viral persistence and infectivity in permafrost, and assessments of human exposure to the enormous viral diversity present in the environment. Based on currently available knowledge, we conclude that the risk posed by viruses from thawing permafrost is no greater than viruses in other environments such as temperate soils and aquatic systems.

Indexed as

FreezingPermafrostVirus DiseasesVirusesAnimalsArctic RegionsClimate ChangeHumansclimate changeenvironmental microbiologypermafrost thawviruses

Identifiers

PMID39772968
PMCPMC11834396

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.