Evidence map›Paper›PMID 39772880›Full record

ArticleJournal of biological rhythms2025

Feeding- and Light-Cycle Synergistically Regulate Mouse Blood Pressure Daily Rhythm via

Tianfei Hou, Wen Su, Aaron N Chacon, An-Hsuan Lin, Zhenheng Guo, Ming C Gong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of biological rhythms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Research Progress of BMAL1 in Heart Failure.Journal of the American Heart Association · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Tianfei HouDepartment of Physiology, College of Medicine, University of Kentucky, Lexington, Kentucky.
Wen SuDepartment of Pharmacology and Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, Kentucky.
Aaron N ChaconDepartment of Pharmacology and Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, Kentucky.
An-Hsuan LinDepartment of Physiology, College of Medicine, University of Kentucky, Lexington, Kentucky.
Zhenheng GuoDepartment of Pharmacology and Nutritional Sciences, College of Medicine, University of Kentucky, Lexington, Kentucky.
Ming C GongDepartment of Physiology, College of Medicine, University of Kentucky, Lexington, Kentucky.ORCID 0000-0002-3554-7378

Funding

Targeting GLP-1 receptor as a new chronotherapy against nondipping blood pressure in diabetesR01HL164398 · NHLBI · UNIVERSITY OF KENTUCKY · PI GONG, MING C, GUO, ZHENHENG · 2022 to 2025
$2.8M
Targeting timing of food intake as a novel strategy against disruption of blood pressure circadian rhythm in diabetesR01HL141103 · NHLBI · UNIVERSITY OF KENTUCKY · PI GONG, MING C, GUO, ZHENHENG · 2019 to 2022
$2.5M
Targeting The GLP-1 Receptor As New Chronotherapy Against Nondipping Blood Pressure In DiabetesF31HL162463 · NHLBI · UNIVERSITY OF KENTUCKY · PI CHACON, AARON · 2022 to 2023
$72k
NHLBI NIH HHS F31 HL162463NHLBI NIH HHS R01 HL141103NHLBI NIH HHS R01 HL164398
6 · The paper itself

Abstract

Cardiovascular health requires the orchestration of the daily rhythm of blood pressure (BP), which responds to changes in light exposure and dietary patterns. Whether rhythmic light and feeding can modulate daily BP rhythm directly or via modulating intrinsic core clock gene

Indexed as

ARNTL Transcription FactorsBlood PressureCircadian RhythmFeeding BehaviorLightPhotoperiodAnimalsBaroreflexEatingEnergy MetabolismHeart RateMaleMiceMice, Inbred C57BLMice, KnockoutMotor ActivityARNTL Transcription FactorsBmal1 protein, mouseNorepinephrinebaroreflexblood pressure daily rhythmBmal1heart rate variabilitylight–dark cyclenorepinephrinesympathetic nervous systemtime-restricted feeding

Identifiers

PMID39772880
PMCPMC11835536

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.