Evidence map›Paper›PMID 39772874›Full record

ArticlemSphere2025

Establishing a new human pneumococcal standard reference serum, MPRSS-01.

Joseph M Antonello, Rocio D Murphy, Chitrananda Abeygunawardana, Juliana C Malinverni, Rajam Gowrisankar, Tina Green, Rebecca Greway, Jenna Schmauch, Adrienne Howlett, Cyrille J Bonhomme and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in mSphere, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Joseph M AntonelloMerck & Co., Inc., Rahway, New Jersey, USA.ORCID 0000-0003-0160-7456
Rocio D MurphyMerck & Co., Inc., Rahway, New Jersey, USA.
Chitrananda AbeygunawardanaMerck & Co., Inc., Rahway, New Jersey, USA.
Juliana C MalinverniMerck & Co., Inc., Rahway, New Jersey, USA.
Rajam GowrisankarMerck & Co., Inc., Rahway, New Jersey, USA.
Tina GreenPPD Vaccine Sciences, part of Thermo Fisher Scientific, Richmond, Virginia, USA.
Rebecca GrewayPPD Vaccine Sciences, part of Thermo Fisher Scientific, Richmond, Virginia, USA.
Jenna SchmauchPPD Vaccine Sciences, part of Thermo Fisher Scientific, Richmond, Virginia, USA.
Adrienne HowlettPPD Vaccine Sciences, part of Thermo Fisher Scientific, Richmond, Virginia, USA.
Cyrille J BonhommePPD Vaccine Sciences, part of Thermo Fisher Scientific, Richmond, Virginia, USA.
Katrina M NolanMerck & Co., Inc., Rahway, New Jersey, USA.ORCID 0000-0001-5030-7930

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Measuring the immunogenicity of pneumococcal vaccines involves the use of immunoassays to measure serotype-specific immunoglobulin G (IgG) antibody levels post-vaccination with the current

Indexed as

Antibodies, BacterialImmunoglobulin GPneumococcal VaccinesStreptococcus pneumoniaeAdultHumansReference StandardsSerogroup23-valent pneumococcal capsular polysaccharide vaccineAntibodies, BacterialImmunoglobulin GPneumococcal Vaccines007spMPRSS-01pneumococcal standard referencepneumococcal vaccine standardization

Identifiers

PMID39772874
PMCPMC11774022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.