Evidence map›Paper›PMID 39772832›Full record

ArticleJCO precision oncology2025

Molecular Profiling of Biliary Tract Cancers in African American and Caucasian Patients.

Zishuo Ian Hu, Dean C Pavlick, Jeffrey S Ross, Sunyoung S Lee, Madhulika Eluri, Milind Javle

Abstract read
In one paragraph

Article in JCO precision oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zishuo Ian HuMD Anderson Cancer Center, Houston, TX.ORCID 0009-0009-8605-0036
Dean C PavlickFoundation Medicine, Cambridge, MA.ORCID 0000-0001-6075-6246
Jeffrey S RossUpstate Medical University, Syracuse, NY.ORCID 0000-0001-8494-2596
Sunyoung S LeeMD Anderson Cancer Center, Houston, TX.
Madhulika EluriMD Anderson Cancer Center, Houston, TX.
Milind JavleMD Anderson Cancer Center, Houston, TX.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeBiliary tract cancers (BTCs) include intrahepatic cholangiocarcinoma (ICC), extrahepatic cholangiocarcinoma (ECC), and gallbladder cancers. BTCs have a number of genomic alterations, including isocitrate dehydrogenase 1 (

methodsBTC patients from AA and Caucasian patients from the Foundation Medicine and AACR GENIE databases were retrospectively reviewed. BTCs were divided into ICC, ECC, and GBCs in the Foundation Medicine database. BTCs were divided into cholangiocarcinomas and GBCs in the AACR GENIE database.

resultsThe mean age of AA patients with BTCs was lower compared with Caucasians.

conclusionThe results of this study suggest that significant genomic differences exist between races and warrant further investigation.

Indexed as

Biliary Tract NeoplasmsBlack or African AmericanWhiteAdultAgedCholangiocarcinomaFemaleHumansMaleMiddle AgedMutationReceptor, Fibroblast Growth Factor, Type 2Retrospective StudiesUnited StatesReceptor, Fibroblast Growth Factor, Type 2

Identifiers

PMID39772832
PMCPMC11723491

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.