Evidence map›Paper›PMID 39772807›Full record

ArticleOpen biology2025

Structure of WzxE the lipid III flippase for Enterobacterial Common Antigen polysaccharide.

Audrey Le Bas, Bradley R Clarke, Tanisha Teelucksingh, Micah Lee, Kamel El Omari, Andrew M Giltrap, Stephen A McMahon, Hui Liu, John H Beale, Vitaliy Mykhaylyk and 13 more

Abstract read
In one paragraph

Article in Open biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. ThemBio · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Audrey Le BasRosalind Franklin Institute, Harwell Campus, Didcot, UK.ORCID 0000-0002-1100-6833
Bradley R ClarkeDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada.
Tanisha TeelucksinghDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada.
Micah LeeDivision of Structural Biology, University of Oxford, Roosevelt Drive, Oxford, UK.
Kamel El OmariDiamond Light Source, Harwell Science and Innovation Campus, Didcot, UK.
Andrew M GiltrapRosalind Franklin Institute, Harwell Campus, Didcot, UK.
Stephen A McMahonBiomedical Sciences Research Complex, North Haugh, University of St Andrews, St Andrews, UK.
Hui LiuBiomedical Sciences Research Complex, North Haugh, University of St Andrews, St Andrews, UK.
John H BealeDiamond Light Source, Harwell Science and Innovation Campus, Didcot, UK.ORCID 0000-0003-1171-2428
Vitaliy MykhaylykDiamond Light Source, Harwell Science and Innovation Campus, Didcot, UK.
Ramona DumanDiamond Light Source, Harwell Science and Innovation Campus, Didcot, UK.
Neil G PatersonDiamond Light Source, Harwell Science and Innovation Campus, Didcot, UK.
Philip N WardRosalind Franklin Institute, Harwell Campus, Didcot, UK.ORCID 0000-0003-2546-3426
Peter J HarrisonMembrane Protein Laboratory, Diamond Light Source, Research Complex at Harwell, Didcot, UK.ORCID 0000-0001-5167-0547
Miriam WeckenerRosalind Franklin Institute, Harwell Campus, Didcot, UK.
Els PardonStructural Biology Brussels, Vrije Universiteit Brussel (VUB), Pleinlaan 2, Brussels B-1050, Belgium.
Jan SteyaertStructural Biology Brussels, Vrije Universiteit Brussel (VUB), Pleinlaan 2, Brussels B-1050, Belgium.
Huanting LiuBiomedical Sciences Research Complex, North Haugh, University of St Andrews, St Andrews, UK.
Andrew QuigleyMembrane Protein Laboratory, Diamond Light Source, Research Complex at Harwell, Didcot, UK.ORCID 0000-0002-5022-9845
Benjamin G DavisRosalind Franklin Institute, Harwell Campus, Didcot, UK.
Armin WagnerDiamond Light Source, Harwell Science and Innovation Campus, Didcot, UK.
Chris WhitfieldDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Ontario, Canada.
James H NaismithRosalind Franklin Institute, Harwell Campus, Didcot, UK.ORCID 0000-0001-6744-5061

Funding

CIHREngineering and Physical Sciences Research Council (EPSRC)European Strategy Forum on Research Infrastructures (ESFRI)FWOWellcome Trust
6 · The paper itself

Abstract

The enterobacterial common antigen (ECA) is conserved in Gram-negative bacteria of the

Indexed as

Escherichia coliEscherichia coli ProteinsModels, MolecularAntigens, BacterialArginineCrystallography, X-RayProtein BindingProtein ConformationAntigens, BacterialArginineenterobacterial common antigenEscherichia coli Proteinscell wallenterobacterial common antigenflippaselipid IIImembrane proteinoligosaccharides

Identifiers

PMID39772807
PMCPMC11706664

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.