Evidence map›Paper›PMID 39772511›Full record

ArticleAnalytical chemistry2025

Dissociation of Macromolecules in Laser-Heated Droplets Monitored by CD-MS.

Hua Pan, Shelby M Klein, Akalanka Gunaratne, Martin F Jarrold, David E Clemmer

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Analytical chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Hua PanDepartment of Chemistry, Indiana University, 800 Kirkwood Avenue, Bloomington, Indiana 47401, United States.ORCID 0009-0008-6707-8503
Shelby M KleinDepartment of Chemistry, Indiana University, 800 Kirkwood Avenue, Bloomington, Indiana 47401, United States.
Akalanka GunaratneDepartment of Chemistry, Indiana University, 800 Kirkwood Avenue, Bloomington, Indiana 47401, United States.
Martin F JarroldDepartment of Chemistry, Indiana University, 800 Kirkwood Avenue, Bloomington, Indiana 47401, United States.ORCID 0000-0001-7084-176X
David E ClemmerDepartment of Chemistry, Indiana University, 800 Kirkwood Avenue, Bloomington, Indiana 47401, United States.ORCID 0000-0003-4039-1360

Funding

Developing High-Resolution Ion Mobility Spectrometry-Charge Detection-Mass Spectrometry for Rapid Analysis in the Megadalton to Gigadalton RegimeR01GM131100 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI CLEMMER, DAVID E., JARROLD, MARTIN F · 2019 to 2022
$2.1M
Characterizing proteasome-substrate interactions by mass spectrometry proteomicsR01GM135264 · NIGMS · TRUSTEES OF INDIANA UNIVERSITY · PI CLEMMER, DAVID E., MATOUSCHEK, ANDREAS · 2020 to 2024
$1.4M
NIGMS NIH HHS R01 GM131100NIGMS NIH HHS R01 GM135264
6 · The paper itself

Abstract

Charge detection mass spectrometry (CD-MS) is used to monitor the dissociation of large (300 kDa to 20 MDa) protein complexes in droplets heated with a 10.6 μm CO

Indexed as

Glutamate DehydrogenaseLasersMacromolecular SubstancesSpectrometry, Mass, Electrospray IonizationCapsid ProteinsHepatitis B virusHot TemperatureHumansCapsid ProteinsGlutamate DehydrogenaseMacromolecular Substances

Identifiers

PMID39772511
PMCPMC11800163

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.