ArticleACS sensors2025
Infrared Spectroscopic Electronic Noses: An Innovative Approach for Exhaled Breath Sensing.
Article in ACS sensors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Machine Learning-Based Profiling of Urinary Volatile Organic Compounds Reveals Distinct Diagnostic Signatures for Gastric Cancer.Cancer medicine · 2026Article
- Trends in vibrational spectroscopy on optical waveguides.Analytical and bioanalytical chemistry · 2026Review
Corrections and comments
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Authors and funding
17 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gastric cancer remains a leading cause of cancer-related mortality, requiring the urgent development of innovative diagnostic tools for early detection. This study presents an integrated infrared spectroscopic electronic nose system, a novel device that combines infrared (IR) spectroscopy and electronic nose (eNose) concepts for analyzing volatile organic compounds (VOCs) in exhaled breath. This system was calibrated using relevant gas mixtures and then tested during a feasibility study involving 26 gastric cancer patients and 32 healthy controls using chemometric analyses to distinguish between exhaled breath profiles. The obtained results demonstrated that the integration of IR spectroscopy and eNose technologies significantly enhanced the accuracy of VOCs fingerprinting via principal component analysis (PCA) and partial least-squares-discriminant analysis (PLS-DA). Distinct differences between the study groups were revealed with an accuracy of prediction of 0.96 in exhaled breath samples. This combined system offers a high sensitivity and specificity and could potetially facilitate rapid on-site testing rendering the technology an accessible option for early screening particularly in underserved populations.
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