Evidence map›Paper›PMID 39772247›Full record

ArticleViruses2024

Tracing the Dispersal Pathway of HIV-1 Subtype C to Bahia: Phylogenetic Connections to Southern Brazil.

Daniel Polita, Laise de Moraes, Marta Giovanetti, Filipe Ferreira de Almeida Rego, Luciane Amorim Santos, Dennis Maletich Junqueira, Ricardo Khouri

Abstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Daniel PolitaPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica Toxicológica (PPGBTox), Laboratório de Bioinformática e Evolução Viral, Universidade Federal de Santa Maria (UFSM), Santa Maria 97105-900, Rio Grande do Sul, Brazil.ORCID 0009-0001-8404-4793
Laise de MoraesInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, Rua Waldemar Falcão, 121, Candeal, Salvador 40296-710, Bahia, Brazil.ORCID 0000-0001-9095-5860
Marta GiovanettiSciences and Technologies for Sustainable Development and One Health, University of Campus Bio-Medico, 00128 Rome, Italy.ORCID 0000-0002-5849-7326
Filipe Ferreira de Almeida RegoEscola Bahiana de Medicina e Saúde Pública, Avenida Dom João VI, 275, Brotas, Salvador 40290-000, Bahia, Brazil.ORCID 0000-0002-6102-6672
Luciane Amorim SantosInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, Rua Waldemar Falcão, 121, Candeal, Salvador 40296-710, Bahia, Brazil.ORCID 0000-0003-0261-3495
Dennis Maletich JunqueiraPrograma de Pós-Graduação em Ciências Biológicas: Bioquímica Toxicológica (PPGBTox), Laboratório de Bioinformática e Evolução Viral, Universidade Federal de Santa Maria (UFSM), Santa Maria 97105-900, Rio Grande do Sul, Brazil.ORCID 0000-0003-1576-484X
Ricardo KhouriInstituto Gonçalo Moniz, Fundação Oswaldo Cruz, Rua Waldemar Falcão, 121, Candeal, Salvador 40296-710, Bahia, Brazil.

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 001Fundação de Amparo à Pesquisa do Estado da Bahia APP0032/2016National Council for Scientific and Technological Development 65083/2015-8
6 · The paper itself

Abstract

The HIV-1 epidemic in Brazil is predominantly characterized by subtype B, except in the southern states, where subtype C (HIV-1C) is more prevalent. Continuous monitoring of this profile is essential to maintain an accurate understanding of the molecular landscape of the HIV epidemic in Brazil. In this study, we isolated and sequenced seven new HIV-1C strains from the state of Bahia, located in the Northeast region of Brazil. To reconstruct the phylogenetic history of HIV-1C in the Northeast and investigate its connections with other regions of the country and globally, we first compiled a dataset of 3631 HIV-1C sequences from Brazil, Africa, and Europe. As expected, most of the new HIV-1C sequences from Bahia (n = 6) clustered within the well-known Brazilian clade. However, one sequence from Bahia clustered within the African clade, suggesting a possible new introduction of HIV-1C into Brazil. Furthermore, our findings indicate that the HIV-1C cases in Bahia likely originated from southern states, particularly Santa Catarina. This study provides valuable insights into the molecular profile of the HIV epidemic in Brazil, expanding our understanding of HIV-1C beyond the Southern region.

Indexed as

HIV-1HIV InfectionsPhylogenyBrazilFemaleGenotypeHumansMaleBahiaBrazilepidemicsHIV-1molecular phylogeneticsSubtype Ctransmission of infectious disease

Identifiers

PMID39772247
PMCPMC11680314

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.