ArticleViruses2024
Serological Evidence of Cryptic Rift Valley Fever Virus Transmission Among Humans and Livestock in Central Highlands of Kenya.
Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Early outbreak detection in endemic settings using a novel method applied to sparse Rift Valley fever incidence data.Scientific reports · 2026Article
- Understanding the Rift Valley fever exposure risk: A comparative perspective from a multi-country study in East and Central Africa, 2021-24.PLoS neglected tropical diseases · 2026Article
- A Cross-Sectional Study of Rift Valley Fever Exposure in Humans and Livestock in Southwestern Uganda Using a One Health Approach: Evidence of Elevated Seroprevalence Outside Recognized Outbreak Periods.Pathogens (Basel, Switzerland) · 2026Article
- Human and livestock exposure to Rift Valley fever virus and Coxiella burnetii in Eastern Ethiopia: a One Health cross-sectional study.Tropical medicine and health · 2026Article
- Hyperendemicity of Rift Valley Fever in Southwestern Uganda Associated With the Rapidly Evolving Lineage C Viruses.The Journal of infectious diseases · 2026Article
- Seroprevalence of Crimean-Congo Hemorrhagic Fever and Rift Valley Fever Viruses Among Ruminants in Nigeria: A Descriptive Epizootiological Analysis.Pathogens (Basel, Switzerland) · 2025Article
- Rift Valley Fever Virus Transmission During an Unreported Outbreak Among People and Livestock in South-Central Tanzania.Viruses · 2025Article
- Have you heard of Rift Valley fever? Findings from a multi-country study in East and Central Africa.PloS one · 2025Article
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Authors and funding
19 authors.
Funding
Abstract
Although the highlands of East Africa lack the geo-ecological landmarks of Rift Valley fever (RVF) disease hotspots to participate in cyclic RVF epidemics, they have recently reported growing numbers of small RVF clusters. Here, we investigated whether RVF cycling occurred among livestock and humans in the central highlands of Kenya during inter-epidemic periods. A 2-year prospective hospital-based study among febrile patients (March 2022-February 2024) in Murang'a County of Kenya was followed by a cross-sectional human-animal survey. A total of 1468 febrile patients were enrolled at two clinics and sera tested for RVF virus RNA and antiviral antibodies. In the cross-sectional study, humans (n = 282) and livestock (n = 706) from randomly selected households were tested and questionnaire data were used to investigate sociodemographic and environmental risk factors by multivariate logistic regression. No human (n = 1750) or livestock (n = 706) sera tested positive for RVFV RNA. However, 4.4% livestock and 2.0% humans tested positive for anti-RVFV IgG, including 0.27% febrile patients who showed four-fold IgG increase and 2.4% young livestock (<12 months old), indicating recent virus exposure. Among humans, the odds of RVF exposure increased significantly (
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