Evidence map›Paper›PMID 39772231›Full record

ArticleViruses2024

Genetic Diversity and Epidemiology of Enteroviruses and Rhinoviruses in Children Hospitalized with Acute Respiratory Infections in Novosibirsk, Russia (2023-2024).

Alina R Nokhova, Tereza A Saroyan, Mariya V Solomatina, Tatyana A Gutova, Anastasiya A Derko, Nikita A Dubovitskiy, Tatyana A Murashkina, Kirill A Sharshov, Alexander M Shestopalov, Olga G Kurskaya

Abstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Alina R NokhovaFederal Research Center of Fundamental and Translational Medicine, Novosibirsk 630060, Russia.ORCID 0000-0002-7891-5847
Tereza A SaroyanFederal Research Center of Fundamental and Translational Medicine, Novosibirsk 630060, Russia.
Mariya V SolomatinaFederal Research Center of Fundamental and Translational Medicine, Novosibirsk 630060, Russia.
Tatyana A GutovaFederal Research Center of Fundamental and Translational Medicine, Novosibirsk 630060, Russia.
Anastasiya A DerkoFederal Research Center of Fundamental and Translational Medicine, Novosibirsk 630060, Russia.ORCID 0000-0002-5984-0819
Nikita A DubovitskiyFederal Research Center of Fundamental and Translational Medicine, Novosibirsk 630060, Russia.ORCID 0000-0002-7780-1485
Tatyana A MurashkinaFederal Research Center of Fundamental and Translational Medicine, Novosibirsk 630060, Russia.
Kirill A SharshovFederal Research Center of Fundamental and Translational Medicine, Novosibirsk 630060, Russia.
Alexander M ShestopalovFederal Research Center of Fundamental and Translational Medicine, Novosibirsk 630060, Russia.
Olga G KurskayaFederal Research Center of Fundamental and Translational Medicine, Novosibirsk 630060, Russia.

Funding

Russian Science Foundation 23-24-00492
6 · The paper itself

Abstract

Rhinoviruses and respiratory enteroviruses remain among the leading causes of acute respiratory infections, particularly in children. Little is known about the genetic diversity of enteroviruses and rhinoviruses in pediatric patients with acute respiratory infections in Russia. We assessed the prevalence of human rhinoviruses/enteroviruses (HRV/EV) in 1992 children aged 0 to 17 years hospitalized with acute respiratory infections during the 2023-2024 epidemic season using PCR. The detection rate of HRV/EV was 11% (220/1992). We performed typing of 58 HRV and 28 EV viruses by partial sequencing of the VP1 gene. Rhinovirus A was the most common among HRV, followed by rhinovirus C; rhinovirus B was detected in only three cases. Enteroviruses were represented by all four species, with the EV-D68 genotype being the most frequently detected. Phylogenetic analysis of the VP1 fragment of EV-D68 showed that all our sequences belonged to the B3 subclade. We identified the first case of EV-C105 infection in Russia in a two-year-old girl hospitalized with pneumonia. Phylogenetically, the Novosibirsk strain EV-C105 was closely related to a strain discovered in France in 2018. This research helped to fill a critical gap in understanding the epidemiological landscape of HRV/EV in pediatric populations within Russia.

Indexed as

EnterovirusEnterovirus InfectionsGenetic VariationGenotypeHospitalizationPhylogenyPicornaviridae InfectionsRespiratory Tract InfectionsRhinovirusAdolescentChildChild, PreschoolFemaleHumansInfantInfant, NewbornenterovirusesEV-C105EV-D68EV typingPicornaviridaerhinoviruses

Identifiers

PMID39772231
PMCPMC11680272

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.