Evidence map›Paper›PMID 39772194›Full record

ArticleViruses2024

Low Prevalence of SARS-CoV-2 in Farmed and Free-Ranging White-Tailed Deer in Florida.

Savannah G Grace, Kristen N Wilson, Rayann Dorleans, Zoe S White, Ruiyu Pu, Natasha N Gaudreault, Konner Cool, Juan M Campos Krauer, Laura E Franklin, Bambi C Clemons and 5 more

Abstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Savannah G GraceDepartment of Wildlife Ecology and Conservation, University of Florida, Gainesville, FL 32611, USA.
Kristen N WilsonDepartment of Wildlife Ecology and Conservation, University of Florida, Gainesville, FL 32611, USA.
Rayann DorleansDepartment of Wildlife Ecology and Conservation, University of Florida, Gainesville, FL 32611, USA.
Zoe S WhiteDepartment of Wildlife Ecology and Conservation, University of Florida, Gainesville, FL 32611, USA.
Ruiyu PuEmerging Pathogens Institute, University of Florida, Gainesville, FL 32610, USA.
Natasha N GaudreaultDepartment of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA.ORCID 0000-0002-7195-785X
Konner CoolDepartment of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA.ORCID 0000-0003-3666-0214
Juan M Campos KrauerDepartment of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32608, USA.ORCID 0000-0002-7098-731X
Laura E FranklinDepartment of Wildlife Ecology and Conservation, University of Florida, Gainesville, FL 32611, USA.
Bambi C ClemonsFish and Wildlife Research Institute, Florida Fish and Wildlife Conservation Commission, Gainesville, FL 32601, USA.
Kuttichantran SubramaniamEmerging Pathogens Institute, University of Florida, Gainesville, FL 32610, USA.
Juergen A RichtDepartment of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA.ORCID 0000-0001-7308-5672
John A LednickyEmerging Pathogens Institute, University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0003-4069-0539
Maureen T LongEmerging Pathogens Institute, University of Florida, Gainesville, FL 32610, USA.ORCID 0000-0001-5337-9024
Samantha M WiselyDepartment of Wildlife Ecology and Conservation, University of Florida, Gainesville, FL 32611, USA.ORCID 0000-0003-1748-4518

Funding

NIAID Centers of Excellence for Influenza Research and Response: Universal Influenza Vaccine Research Activities75N93021C00016 · NIAID · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI WEBBY, RICHARD · 2021 to 2025
$91.4M
Sex-specific effects of obestity on Influenza A virus infection and immunityP20GM130448 · NIGMS · KANSAS STATE UNIVERSITY · PI REVATHI GOVIND · 2020 to 2026
$15.8M
Florida Legislature LBR2199National Institutes of General Medical Sciences P20GM130448NIAID NIH HHS 75N93021C00016NIGMS NIH HHS P20 GM130448State of Kansas, National Bio and Agro-Defense Facility Transition Fund NBAF
6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been detected in multiple animal species, including white-tailed deer (WTD), raising concerns about zoonotic transmission, particularly in environments with frequent human interactions. To understand how human exposure influences SARS-CoV-2 infection in WTD, we compared infection and exposure prevalence between farmed and free-ranging deer populations in Florida. We also examined the timing and viral variants in WTD relative to those in Florida's human population. Between 2020 and 2022, we collected respiratory swabs (N = 366), lung tissue (N = 245), retropharyngeal lymph nodes (N = 491), and serum specimens (N = 381) from 410 farmed and 524 free-ranging WTD. Specimens were analyzed using RT-qPCR for infection and serological assays for exposure. SARS-CoV-2 infection was detected in less than 1% of both northern Florida farmed (0.85%) and free-ranging (0.76%) WTD. No farmed deer possessed virus-neutralizing antibodies, while one free-ranging WTD tested positive for SARS-CoV-2 antibodies (3.45%). Viral sequences in infected WTD matched peaks in human cases and circulating variants, indicating human-to-deer spillover but at a lower frequency than reported elsewhere. Our findings suggest a reduced risk of SARS-CoV-2 spillover to WTD in northern Florida compared to other regions, highlighting the need for further research on transmission dynamics across North America.

Indexed as

COVID-19DeerSARS-CoV-2AnimalsAnimals, WildFloridaHumansPrevalenceZoonosesFloridaSARS-CoV-2white-tailed deerzoonotic transmission

Identifiers

PMID39772194
PMCPMC11680379

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.