Evidence map›Paper›PMID 39772169›Full record

ArticleViruses2024

Construction of a Macrophage-Tropic Subtype C HIV-1-mGreenLantern Reporter Virus for Studies on HIV-1 Replication and the Impact of Methamphetamine.

Dina Mofed, Angelo Mandarino, Xuhong Wu, Yuekun Lang, Anjali Gowripalan, Ganjam V Kalpana, Vinayaka R Prasad

Erratum issuedAbstract read
In one paragraph

Article in Viruses, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Dina MofedDepartments of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Angelo MandarinoDepartments of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.ORCID 0000-0001-9349-4326
Xuhong WuDepartment of Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Yuekun LangDepartments of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.ORCID 0000-0002-4427-5271
Anjali GowripalanDepartments of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.ORCID 0000-0002-3905-5485
Ganjam V KalpanaDepartment of Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA.ORCID 0000-0003-4111-0604
Vinayaka R PrasadDepartments of Microbiology and Immunology, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

Funding

Training in HIV/AIDS Pathogenesis; Basic and Translational ResearchT32AI007501 · NIAID · YESHIVA UNIVERSITY · PI PRASAD, VINAYAKA R. · 1995 to 2024
$6.6M
CCL2-CCR2b signaling in HIV-1 fitness and disease; Role of host genetic polymorphismsR01AI153008 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI PRASAD, VINAYAKA R. · 2020 to 2024
$3.0M
NIAID NIH HHS R01 AI153008NIAID NIH HHS T32 AI007501NIH HHS R01 AI153008
6 · The paper itself

Abstract

HIV-1 subtype C viruses are responsible for 50% of global HIV burden. However, nearly all currently available reporter viruses widely used in HIV research are based on subtype B. We constructed and characterized a replication-competent HIV-1 subtype C reporter virus expressing mGreenLantern. mGreenLantern sequences were inserted in-frame with Nef ATG in HIV-1

Indexed as

Genes, ReporterHIV-1MacrophagesMethamphetamineVirus ReplicationCell LineChemokine CCL2HEK293 CellsHIV InfectionsHumansnef Gene Products, Human Immunodeficiency VirusViral TropismChemokine CCL2Methamphetaminenef Gene Products, Human Immunodeficiency VirusCCL2methamphetaminereplication competent HIV-1 reportersubtype C HIV-1

Identifiers

PMID39772169
PMCPMC11680207

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.