Evidence map›Paper›PMID 39772106›Full record

ReviewVaccines2024

Boosting Vaccine Research: The 16-Year Journey of TRANSVAC Vaccine Infrastructure.

William Martin, Catarina Luís, Stefan Jungbluth, Monika Slezak, Frank A W Verreck, Holger Spiegel, Carlos A Guzman, António Roldão, Manuel J T Carrondo, Peter Van der Ley and 6 more

Abstract readReview
In one paragraph

Review in Vaccines, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

William MartinEuropean Vaccine Initiative (EVI), 69115 Heidelberg, Germany.ORCID 0000-0003-4839-1752
Catarina LuísEuropean Vaccine Initiative (EVI), 69115 Heidelberg, Germany.
Stefan JungbluthEuropean Vaccine Initiative (EVI), 69115 Heidelberg, Germany.ORCID 0000-0002-8728-5410
Monika SlezakEuropean Vaccine Initiative (EVI), 69115 Heidelberg, Germany.ORCID 0000-0002-6832-5157
Frank A W VerreckBiomedical Primate Research Centre (BPRC), 2288 GJ Rijswijk, The Netherlands.ORCID 0000-0002-4441-5000
Holger SpiegelFraunhofer Institute for Molecular Biology and Applied Ecology IME, 52074 Aachen, Germany.
Carlos A GuzmanDepartment of Vaccinology and Applied Microbiology, Helmholtz Centre for Infection Research (HZI), 38124 Braunschweig, Germany.ORCID 0000-0002-2913-5254
António RoldãoiBET-Instituto de Biologia Experimental e Tecnológica, 2781-901 Oeiras, Portugal.ORCID 0000-0003-0414-4899
Manuel J T CarrondoiBET-Instituto de Biologia Experimental e Tecnológica, 2781-901 Oeiras, Portugal.
Peter Van der LeyIntravacc BV, 3721 MA Bilthoven, The Netherlands.
Joaquim SegalésUnitat Mixta d'Investigació IRTA UAB en Sanitat Animal, Centre de Recerca en Sanitat Animal (CReSA), Departament de Sanitat i Anatomia Animals, Facultat de Veterinària, Campus de la Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain.ORCID 0000-0002-1539-7261
Hazel M DockrellDepartment of Infection Biology, London School of Hygiene & Tropical Medicine, London WC1E 7HT, UK.
Mei Mei HoMedicines and Healthcare Products Regulatory Agency (MHRA), Potters Bar EN6 3QG, UK.
Gabriel K PedersenDepartment of Infectious Disease Immunology, Statens Serum Institut, Artillerivej 5, 2300 Copenhagen, Denmark.
Maria LawrenzVaccine Formulation Institute (VFI), Plan-les-Ouates, 1228 Geneva, Switzerland.ORCID 0000-0003-4762-9132
Ole F OlesenEuropean Vaccine Initiative (EVI), 69115 Heidelberg, Germany.ORCID 0000-0002-3025-2466

Funding

European Commission 101046133European Commission 730964European Commission FP7-INFRASTRUCTURES-2008-228403
6 · The paper itself

Abstract

TRANSVAC represents a long-running effort to accelerate the development of novel vaccines by integrating institutions from across Europe under a single collaborative framework. This initiative has empowered the global vaccine community since 2009 including contributing toward the development and optimization of vaccine candidates as well as the provision of new adjuvants, research protocols, and technologies. Scientific services were provided in support of 88 different vaccine development projects, and 400 professionals attended TRANSVAC training events on various vaccine-related topics. Here, we review the accomplishments of the TRANSVAC consortia and analyze the continued needs of academic and industrial vaccine developers in Europe. The findings highlight the benefits of coordination across different sectors, both through research infrastructures such as TRANSVAC and other mechanisms, to address the current and future global health challenges and ensure that European vaccine developers have the support required to successfully compete in the global market.

Indexed as

research and developmentresearch infrastructurevaccine

Identifiers

PMID39772106
PMCPMC11680270

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.