A NIRS-Based Technique for Monitoring Brain Tissue Oxygenation in Stroke Patients.

Stroke is a global health issue caused by reduced blood flow to the brain, which leads to severe motor disabilities. Measuring oxygen levels in the brain tissue is crucial for understanding the severity and evolution of stroke. While CT or fMRI scans are preferred for confirming a stroke due to their high sensitivity, Near-Infrared Spectroscopy (NIRS)-based systems could be an alternative for monitoring stroke evolution. This study explores the potential of fNIRS signals to assess brain tissue in chronic stroke patients along with rehabilitation therapy. To study the feasibility of this proposal, ten healthy subjects and three stroke patients participated. For signal acquisition, two NIRS sensors were placed on the forehead of the subjects, who were asked to remain in a resting state for 5 min, followed by a 30 s motor task for each hand, which consists of opening and closing the hand at a steady pace, with a 1 min rest period in between. Acomplete protocol for placing sensors and a signal processing algorithm are proposed. In healthy subjects, a measurable change in oxygen saturation was found, with statistically significant differences (females