Evidence map›Paper›PMID 39771760›Full record

ArticleSensors (Basel, Switzerland)2024

Using Heart Rate and Behaviors to Predict Effective Intervention Strategies for Children on the Autism Spectrum: Validation of a Technology-Based Intervention.

Amarachi Emezie, Rima Kamel, Morgan Dunphy, Amanda Young, Heather J Nuske

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Beyond the Outburst: Charting a New Frontier for Understanding and Treating Irritability in Autistic Adults.Autism research : official journal of the International Society for Autism Research · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Amarachi EmezieDepartment of Psychology, University of Pennsylvania, Philadelphia, PA 19104, USA.
Rima KamelDepartment of Psychiatry, Penn Center for Mental Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Morgan DunphyDepartment of Psychiatry, Penn Center for Mental Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0009-0007-3701-2979
Amanda YoungMayo Clinic, Mayo Eugenio Litta Children's Hospital, Rochester, MN 55902, USA.
Heather J NuskeDepartment of Psychiatry, Penn Center for Mental Health, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.ORCID 0000-0001-6618-3768

Funding

Reducing Challenging Behaviors In Children With Autism Through Digital HealthK01MH120509 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI NUSKE, HEATHER J · 2020 to 2024
$773k
NIMH NIH HHS K01 MH120509NIMH NIH HHS K01MH120509
6 · The paper itself

Abstract

Many children on the autism spectrum engage in challenging behaviors, like aggression, due to difficulties communicating and regulating their stress. Identifying effective intervention strategies is often subjective and time-consuming. Utilizing unobservable internal physiological data to predict strategy effectiveness may help simplify this process for teachers and parents. This study examined whether heart rate data can predict strategy effectiveness. Teachers and coders from the research team recorded behavioral and heart rate data over three months for each participating student on the autism spectrum using the KeepCalm app, a platform that provides in-the-moment strategy suggestions based on heart rate and past behavioral data, across 226 instances of strategy interventions. A binary logistic regression was performed to assess whether heart rate reduction, time to return to heart rate baseline, and documented skills and challenging behaviors predicted strategy effectiveness. Results suggested that heart rate reduction may be a significant predictor, and supported the existing practice of using behavioral patterns as proxies for strategy effectiveness. Additional analyses indicate proactive strategies are more effective and are associated with greater reduction in heart rate, relative to reactive strategies. Further exploration of how internal physiological data can complement observable behaviors in assessing intervention strategy effectiveness is warranted given the novelty of our findings.

Indexed as

Autism Spectrum DisorderHeart RateChildFemaleHumansMaleMobile Applicationschallenging behaviorsdigital mental healthheart rate trackingintervention strategy effectivenessobservable behavioral dataunobservable internal physiological data

Identifiers

PMID39771760
PMCPMC11678940

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.