Evidence map›Paper›PMID 39771564›Full record

ReviewPharmaceutics2024

The Role of Extracellular Vesicles in the Development and Treatment of Psoriasis: Narrative Review.

Bin Tang, Yang Bi, Xuwei Zheng, Yujie Yang, Xiaobing Huang, Kexin Yang, Haixin Zhong, Ling Han, Chuanjian Lu, Haiming Chen

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. TopicalPharmaceutics · 2026
    Article
  2. Exosomes in Psoriasis: From Pathogenic Mechanisms to Therapeutic Innovations.Clinical, cosmetic and investigational dermatology · 2026
    Review
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Bin TangThe Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou 510120, China.
Yang BiThe Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou 510120, China.
Xuwei ZhengShenzhen Hospital (Futian) of Guangzhou University of Chinese Medicine, Shenzhen 518000, China.
Yujie YangThe Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou 510120, China.
Xiaobing HuangHospital of Osteopathy The Third Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangzhou 510378, China.
Kexin YangThe Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou 510120, China.
Haixin ZhongThe Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou 510120, China.
Ling HanThe Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou 510120, China.
Chuanjian LuThe Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou 510120, China.
Haiming ChenThe Second Clinical College of Guangzhou University of Chinese Medicine, Guangzhou 510120, China.ORCID 0009-0006-1756-9991

Funding

Bajian Talents of Guangdong Provincial Hospital of Chinese Medicine BJ2022KY02Chinese Medicinal Scientific Research Project of Guangdong Province 2024401Innovation Team and Talents Cultivation Program of National Administration of Traditional Chinese Medicine ZYYCXTD-C-202204National Natural Science Foundation of China U23A6012 & U20A20397Science and Technology Planning Project of Guangdong Province 2020B1212030006 & 2020B1111170012Science and Technology Planning Project of Guangzhou 202201020353 & 202206080006 & 2024A03J0702Technology Research Projects of State Key laboratory ofDampness Syndrome of Chinese Medi-cine SZ2021ZZ34 & SZ2021ZZ45 & SZ2021ZZ15
6 · The paper itself

Abstract

Psoriasis is a chronic inflammatory polygenic disease with significant impacts on skin and joints, leading to substantial treatment challenges and healthcare costs. The quest for novel therapeutic avenues has recently highlighted extracellular vesicles (EVs) due to their potential as biomarkers and therapeutic agents in autoimmune diseases, including psoriasis. EVs are nano-sized, lipid membrane-bound particles secreted by cells that have emerged as promising tools for targeted drug delivery, owing to their unique structure. This review delves into how EVs, either as mediators of cell communication or via their cargo (such as miRNA), directly participate in the pathology of psoriasis, influencing processes such as immune regulation, cell proliferation, and differentiation. Furthermore, this review explores the innovative application of EVs in psoriasis treatment, both as direct therapeutic agents and as vehicles for drug delivery, offering a novel approach to overcoming the current treatment limitations.

Indexed as

extracellular vesiclenano particlespsoriasistherapyvesicle cargo

Identifiers

PMID39771564
PMCPMC11677080

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.