Evidence map›Paper›PMID 39771549›Full record

ArticlePharmaceutics2024

Concomitant Inhibition and Collaring of Dual-Species Biofilms Formed by

Humaira Parveen, Sayeed Mukhtar, Mona O Albalawi, Syed Khasim, Aijaz Ahmad, Mohmmad Younus Wani

Abstract read
In one paragraph

Article in Pharmaceutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Morphotype-specific susceptibility toMicrobiology spectrum · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Humaira ParveenOrganic and Medicinal Chemistry Research Laboratory, Department of Chemistry, University of Tabuk, Tabuk 71491, Saudi Arabia.ORCID 0000-0001-8365-0014
Sayeed MukhtarOrganic and Medicinal Chemistry Research Laboratory, Department of Chemistry, University of Tabuk, Tabuk 71491, Saudi Arabia.ORCID 0000-0002-5150-9187
Mona O AlbalawiOrganic and Medicinal Chemistry Research Laboratory, Department of Chemistry, University of Tabuk, Tabuk 71491, Saudi Arabia.ORCID 0009-0001-4594-8570
Syed KhasimAdvanced Materials Research Laboratory, Department of Physics, Faculty of Science, University of Tabuk, Tabuk 71491, Saudi Arabia.
Aijaz AhmadDepartment of Clinical Microbiology and Infectious Diseases, Faculty of Health Sciences, School of Pathology, University of the Witwatersrand, Johannesburg 2193, South Africa.ORCID 0000-0003-2845-0727
Mohmmad Younus WaniDepartment of Chemistry, College of Science, University of Jeddah, Jeddah 21589, Saudi Arabia.ORCID 0000-0002-1838-1337

Funding

Deanship of Research and Graduate Studies at University of Tabuk 0078-1444-S
6 · The paper itself

Abstract

BACKGROUND/

objectivesBiofilm-associated infections, particularly those involving Candida auris and Staphylococcus aureus, pose significant challenges in clinical settings due to their resilience and resistance to conventional treatments. This study aimed to synthesize novel triazole derivatives containing a piperazine ring via click chemistry and evaluate their efficacy in disrupting biofilms formed by these pathogens.

methodsTriazole derivatives were synthesized using click chemistry techniques. The antimicrobial activity of the compounds was tested against planktonic cells of

resultsThe compound T3 demonstrated potent antimicrobial activity against planktonic cells of

conclusionsThis study underscores the anti-biofilm properties of novel triazole-piperazine derivatives, particularly T3, against single and dual-species biofilms of

Indexed as

biofilmsclick chemistrydrug resistancephysicochemical propertiestriazole

Identifiers

PMID39771549
PMCPMC11677466

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.