Evidence map›Paper›PMID 39771033›Full record

Trial reportNutrients2024

The Effect of Ingesting Alginate-Encapsulated Carbohydrates and Branched-Chain Amino Acids During Exercise on Performance, Gastrointestinal Symptoms, and Dental Health in Athletes.

Lotte L K Nielsen, Max Norman Tandrup Lambert, Jørgen Jensen, Per Bendix Jeppesen

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lotte L K NielsenDepartment of Clinical Medicine, Aarhus University Hospital, Aarhus University, Palle Juul-Jensens Boulevard 165, 8200 Aarhus, Denmark.ORCID 0009-0007-7691-2670
Max Norman Tandrup LambertDepartment of Clinical Medicine, Aarhus University Hospital, Aarhus University, Palle Juul-Jensens Boulevard 165, 8200 Aarhus, Denmark.
Jørgen JensenDepartment of Physical Performance, Norwegian School of Sports Sciences, 0863 Oslo, Norway.
Per Bendix JeppesenDepartment of Clinical Medicine, Aarhus University Hospital, Aarhus University, Palle Juul-Jensens Boulevard 165, 8200 Aarhus, Denmark.ORCID 0000-0001-8042-7554

Funding

Innovation Fund Denmark 0153-00092B
6 · The paper itself

Abstract

backgroundThis study aimed to compare the effects of a carbohydrate (CHO) hydrogel with (ALG-CP) or without (ALG-C) branched-chain amino acids, and a CHO-only non-hydrogel (CON), on cycling performance. The hydrogels, encapsulated in an alginate matrix, are designed to control CHO release, potentially optimising absorption, increasing substrate utilisation, and reducing gastrointestinal distress as well as carious lesions.

methodsIn a randomised, double-blinded, crossover trial, 10 trained male cyclists/triathletes completed three experimental days separated by ~6 days. During the experimental days, participants completed a standardised 2 h cycling bout (EX1), followed by a time-to-exhaustion (TTE) performance test at W

resultsParticipants cycled ~8.8 (29.6%) and ~5.4 (29.1%) minutes longer during TTE with ALG-CP compared to ALG-C and CON, respectively. TTE was 65.28 ± 2.8 min with ALG-CP, 56.46 ± 10.92 min with ALG-C, and 59.89 ± 11.89 min with CON. Heart rate (HR) was lower during EX1 with ALG-CP (

conclusionsWhile ALG-CP improved performance duration compared to ALG-C and CON, the difference did not reach statistical significance. Additionally, there was a lower HR during the cycling session, alongside a significantly lower level of myoglobin with ALG-CP. These findings suggest that ALG-CP may offer advantages in cycling performance and recovery.

Indexed as

AlginatesAmino Acids, Branched-ChainCross-Over StudiesDietary CarbohydratesAdultAthletesAthletic PerformanceBicyclingBlood GlucoseDietary SupplementsDouble-Blind MethodExerciseGastrointestinal DiseasesHeart RateHumansHydrogelsAlginatesAmino Acids, Branched-ChainBlood GlucoseDietary CarbohydratesHydrogelsalginateathletic performanceBCAAcarbohydratesdental healthgastrointestinal comforthydrogelsrecoveryTTE

Identifiers

PMID39771033
PMCPMC11676411

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.