Evidence map›Paper›PMID 39770992›Full record

ArticleNutrients2024

The Mediating Role of Gut Microbiota on the Association Between Dietary Quality and Cancer-Related Fatigue Among Breast Cancer Patients: A Cross-Sectional Study.

Jianyun He, Lan Cheng, Xinxin Cheng, Yuting Wang, Xiaoxia Lin, Shufang Xia

Abstract read
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jianyun HeWuxi School of Medicine, Jiangnan University, Wuxi 214122, China.
Lan ChengWuxi School of Medicine, Jiangnan University, Wuxi 214122, China.ORCID 0009-0007-1084-7159
Xinxin ChengWuxi School of Medicine, Jiangnan University, Wuxi 214122, China.
Yuting WangWuxi School of Medicine, Jiangnan University, Wuxi 214122, China.
Xiaoxia LinWuxi School of Medicine, Jiangnan University, Wuxi 214122, China.
Shufang XiaWuxi School of Medicine, Jiangnan University, Wuxi 214122, China.

Funding

National Natural Science Foundation of China 81703222
6 · The paper itself

Abstract

objectivesCancer-related fatigue (CRF) is highly prevalent in patients with breast cancer, resulting in undesirable outcomes and even reduced survival rates. This cross-sectional study investigated the relationship between dietary quality and CRF in patients with breast cancer, and the potential role of gut microbiota (GM) in this association.

methodsDietary intake and CRF were evaluated in 342 patients, with 64 fecal samples collected for 16sRNA sequencing and 106 plasma samples for tryptophan (TRP) metabolite determination.

resultsA total of 149 (43.6%) patients experienced CRF, which was significantly associated with low intakes of protein, vitamin A, vitamin E, dietary fiber, phosphorus, magnesium, potassium, iron, and copper (

conclusionsThe presence of CRF in patients with breast cancer might be correlated with inadequate nutrient intake and low dietary quality via GM-dependent pathways.

Indexed as

Breast NeoplasmsDietFatigueGastrointestinal MicrobiomeAdultAgedCross-Sectional StudiesDiet, HealthyFecesFemaleHumansKynurenineMiddle AgedTryptophanKynurenineTryptophanbreast cancercancer-related fatiguedietary qualitygut microbiotanutrients

Identifiers

PMID39770992
PMCPMC11676191

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.