Evidence map›Paper›PMID 39770828›Full record

ArticleMicroorganisms2024

Alterations in Gut Microbiota Composition Are Associated with Changes in Emotional Distress in Children with Obstructive Sleep Apnea.

Chung-Guei Huang, Wan-Ni Lin, Li-Jen Hsin, Yu-Shu Huang, Li-Pang Chuang, Tuan-Jen Fang, Hsueh-Yu Li, Terry B J Kuo, Cheryl C H Yang, Chin-Chia Lee and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Chung-Guei HuangDepartment of Laboratory Medicine, Linkou Main Branch, Chang Gung Memorial Hospital, Taoyuan 33305, Taiwan.ORCID 0000-0002-0598-5684
Wan-Ni LinDepartment of Otorhinolaryngology-Head and Neck Surgery, Linkou Main Branch, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan 33305, Taiwan.ORCID 0000-0001-5782-8835
Li-Jen HsinDepartment of Otorhinolaryngology-Head and Neck Surgery, Linkou Main Branch, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan 33305, Taiwan.ORCID 0000-0001-9201-0270
Yu-Shu HuangSchool of Medicine, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.ORCID 0000-0002-4015-5942
Li-Pang ChuangSchool of Medicine, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.ORCID 0000-0001-5466-8995
Tuan-Jen FangDepartment of Otorhinolaryngology-Head and Neck Surgery, Linkou Main Branch, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan 33305, Taiwan.ORCID 0000-0002-7805-3458
Hsueh-Yu LiDepartment of Otorhinolaryngology-Head and Neck Surgery, Linkou Main Branch, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan 33305, Taiwan.ORCID 0000-0002-9016-8098
Terry B J KuoInstitute of Brain Science, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.
Cheryl C H YangInstitute of Brain Science, National Yang Ming Chiao Tung University, Taipei 112304, Taiwan.
Chin-Chia LeeSchool of Medicine, College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.
Li-Ang LeeDepartment of Otorhinolaryngology-Head and Neck Surgery, Linkou Main Branch, Chang Gung Memorial Hospital, Chang Gung University, Taoyuan 33305, Taiwan.ORCID 0000-0001-8414-595X

Funding

Chang Gung Medical Foundation, Taiwan CORPG3K0242, CORPG3L0481, CMRPG3F1091-3National Science and Technology Council, Taiwan 109-2314-B-182-083-MY3
6 · The paper itself

Abstract

Emerging evidence underscores the pivotal role of the gut microbiota in regulating emotional and behavioral responses via the microbiota-gut-brain axis. This study explores associations between pediatric obstructive sleep apnea (OSA), emotional distress (ED), and gut microbiome alterations before and after OSA treatment. Sixty-six children diagnosed with OSA via polysomnography participated, undergoing adenotonsillectomy alongside routine educational sessions. ED was assessed using the OSA-18 questionnaire, categorizing participants into high ED (scores ≥ 11, 52%) and low ED (scores < 11, 48%) groups. Gut microbiome analysis revealed significant diversity differences, with high ED linked to a reduced Shannon index (

Indexed as

adenotonsillectomychildrendietary profileeducational counselingemotional distressgut microbiomeobstructive sleep apneasleep heart rate

Identifiers

PMID39770828
PMCPMC11677172

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.