Evidence map›Paper›PMID 39770796›Full record

ArticleMicroorganisms2024

Towards Reliable Methodology: Microbiome Analysis of Fresh Frozen vs. Formalin-Fixed Paraffin-Embedded Bladder Tissue Samples: A Feasibility Study.

Dominik Enderlin, Uwe Bieri, Jana Gadient, Yasser Morsy, Michael Scharl, Jan Hendrik Rüschoff, Lukas John Hefermehl, Anna Nikitin, Janine Langenauer, Daniel Stephan Engeler and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Dominik EnderlinDepartment of Urology, University Hospital of Zurich, University of Zurich, 8091 Zurich, Switzerland.
Uwe BieriDepartment of Urology, University Hospital of Zurich, University of Zurich, 8091 Zurich, Switzerland.
Jana GadientDepartment of Urology, University Hospital of Zurich, University of Zurich, 8091 Zurich, Switzerland.
Yasser MorsyDepartment of Gastroenterology and Hepatology, University Hospital of Zurich, University of Zurich, 8091 Zurich, Switzerland.ORCID 0000-0001-8234-1877
Michael ScharlDepartment of Gastroenterology and Hepatology, University Hospital of Zurich, University of Zurich, 8091 Zurich, Switzerland.
Jan Hendrik RüschoffDepartment of Pathology, and Molecular Pathology, University Hospital of Zurich, University of Zurich, 8091 Zurich, Switzerland.ORCID 0000-0002-1936-6606
Lukas John HefermehlDivision of Urology, Department of Surgery, Kantonsspital Baden, 5404 Baden, Switzerland.ORCID 0000-0002-8467-5333
Anna NikitinDivision of Urology, Department of Surgery, Kantonsspital Baden, 5404 Baden, Switzerland.
Janine LangenauerDepartment of Urology, Cantonal Hospital of St. Gallen, School of Medicine, University of St. Gallen, 9007 St. Gallen, Switzerland.
Daniel Stephan EngelerDepartment of Urology, Cantonal Hospital of St. Gallen, School of Medicine, University of St. Gallen, 9007 St. Gallen, Switzerland.
Beat FörsterDepartment of Urology, Kantonsspital Winterthur, 8401 Winterthur, Switzerland.ORCID 0000-0002-7864-408X
Fabian ObrechtDepartment of Urology, Kantonsspital Winterthur, 8401 Winterthur, Switzerland.
Jonathan SurberDepartment of Urology, University Hospital of Zurich, University of Zurich, 8091 Zurich, Switzerland.ORCID 0009-0006-2756-7914
Thomas Paul SchererDepartment of Urology, University Hospital of Zurich, University of Zurich, 8091 Zurich, Switzerland.ORCID 0000-0001-5544-1063
Daniel EberliDepartment of Urology, University Hospital of Zurich, University of Zurich, 8091 Zurich, Switzerland.ORCID 0000-0001-8866-8010
Cédric PoyetDepartment of Urology, University Hospital of Zurich, University of Zurich, 8091 Zurich, Switzerland.

Funding

the Swiss Cancer Research foundation KFS-5308-02-2021-R
6 · The paper itself

Abstract

Studies have shown that the human microbiome influences the response to systemic immunotherapy. However, only scarce data exist on the impact of the urinary microbiome on the response rates of bladder cancer (BC) to local

Indexed as

alpha diversitybladder cancerformalin-fixed paraffin-embeddedfresh frozenmicrobiome

Identifiers

PMID39770796
PMCPMC11677477

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.