ArticleMicroorganisms2024
The Human Nasal Microbiome: A Perspective Study During the SARS-CoV-2 Pandemic in Malta.
Article in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- An NGS-assisted diagnostic workflow for culture-independent detection of bloodstream pathogens and prediction of antimicrobial resistances in sepsis.Frontiers in cellular and infection microbiology · 2025Trial
- Hybrid-sport participation is associated with gut microbiota composition: an exploratory longitudinal study.Frontiers in sports and active living · 2026Article
- SkinDuoInternational journal of molecular sciences · 2025Observational
- Nasal Microbiota Profiling as a Predictive Secondary Tool for COVID-19 Diagnosis: The Critical Role of Taxonomic Resolution.Microorganisms · 2025Article
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Authors and funding
4 authors.
Funding
Abstract
The human respiratory tract is colonized by a complex microbial community that helps maintain respiratory health and plays a crucial role in defending the host from infections. Respiratory viruses have been demonstrated to alter microbiota composition, resulting in opportunistic species expansion, and increasing the disease severity and host susceptibility to bacterial co-infections. This study aims to examine the compositional differences in the nasal microbiota between SARS-CoV-2-infected and non-infected patients. We conducted Oxford Nanopore full-length 16S rRNA sequencing on nasal swabs from 94 COVID-19 negative and 85 COVID-19 positive patients collected during the SARS-CoV-2 pandemic in Malta. Our analysis identified significant alpha and beta diversity differences in the nasal microbiota composition among our study groups. We observed a trend toward decreased microbial richness and evenness in the COVID-Positive cohort with and increased abundance of common nasal opportunistic species including
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Registered trials
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