ReviewMicroorganisms2024
Antibacterial, Antifungal, Antiviral Activity, and Mechanisms of Action of Plant Polyphenols.
Review in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
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Who cites it
39 citing papers in PubMed.
- Flavonoids as Antimicrobial Pesticides: Mechanisms of Action, Formulation Strategies, and Perspectives for Pre- and Postharvest Disease Management.Plants (Basel, Switzerland) · 2026Review
- Bioactive Phenolics fromAntioxidants (Basel, Switzerland) · 2026Article
- Updates on the Strategies to Improve the Anti-Tumor Efficacy of Ferulic Acid.International journal of molecular sciences · 2026Review
- Integrated Chemical Profiling and Biological Assessment ofAntibiotics (Basel, Switzerland) · 2026Article
- Article
- Natural Products as Nutritional Supplements in Human Disease Prevention and Management: From Molecular Mechanisms to Clinical Translation.Nutrients · 2026Review
- Phytogenic synthesis and characterization of silver nanoparticles from Crataegus songarica aqueous extract for comprehensive biological evaluation.Discover nano · 2026Article
- One-pot click synthesis of hybrid triazole-pyridine-functionalized polyphenol derivatives under ultrasound irradiation and their antimicrobial assays.Scientific reports · 2026Article
- Eco-friendly synthesis of silver oxide nanoparticles using Nepeta cataria L. (Lamiaceae) flowers extract: a multifaceted study of their antimicrobial and hemocompatible potential.Scientific reports · 2026Article
- The effectiveness of Annona muricata for improving induced oral candidiasis in gamma-irradiated rats.BMC complementary medicine and therapies · 2026Article
- Antifungal Activity ofInternational journal of molecular sciences · 2026Article
- An Innovative Oral Ex Vivo Biofilm Model for Antimicrobial Investigations.Pathogens (Basel, Switzerland) · 2026Article
- Review on bioactive compounds of medicinal plants with antiviral properties against Newcastle disease virus (NDV).Archives of virology · 2026Review
- Neuro-inflammation Induced by Arsenic: An Insight into Mechanisms and Pathways Involved.Biological trace element research · 2026Review
- Coffee Cascara as a Source of Natural Antimicrobials: Chemical Characterization and Activity Against ESKAPE Pathogens.Molecules (Basel, Switzerland) · 2026Article
- Polyphenols from Byproducts: Their Applications and Health Effects.Antioxidants (Basel, Switzerland) · 2026Review
- Fucoidan and alginate from brown seaweeds: extraction, structural diversity, biocompatibility, biodegradability, and biomedical applications.Frontiers in plant science · 2026Review
- New gel formulation for treating wounds infected with common bacteria isolated from feline wounds in rats.Open veterinary journal · 2026Article
- Effects of dietary garlic oil and black seed oil supplementation on growth performance, immunity, and immune-related gene expression in broiler chickens.Frontiers in veterinary science · 2026Article
- Fermentative valorisation of agri-food residues: optimisation ofFrontiers in bioengineering and biotechnology · 2026Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This review describes the enhanced classification of polyphenols into flavonoids, lignans, phenolic acids, stilbenes, and tannins. Its focus is the natural sources of polyphenols and an in-depth discussion of their antibacterial, antifungal, and antiviral activity. Besides a broad literature overview, this paper contains authors' experimental data according to some daily consumed vegetables such as tomatoes, different varieties of onion, garlic, parsley, and cayenne pepper and the probable relation of these activities to polyphenols. The isolation of polyphenols via conventional and ultrasonic, pressurized liquids and pulse-field extractions, as well as their methods for detection and determination, are interpreted as well. The main mechanisms by which polyphenols inhibit the growth of bacteria, fungi, and viruses, such as protein synthesis, cell membrane destabilization, and ROS production induction, are in focus. Data on polyphenol concentrations and their respective MIC or the inhibition zone diameters of different bacterial and fungal species and suppressing viral replication are depicted. The toxicity of polyphenols in vitro, ex vivo, and in vivo towards microorganisms and human/animal cells, and the safety of the polyphenols applied in clinical and industrial applications are expanded. This review also characterizes the antimicrobial effects of some chemically synthesized polyphenol derivatives. Biotechnological advances are also reported, especially the entrapment of polyphenols in biocompatible nanoparticles to enhance their bioavailability and efficacy. Polyphenols are promising for exploring molecules' novel antimicrobial substances and paving the path for effective novel antimicrobial agents' discovery, taking into consideration their positives and negatives.
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