Evidence map›Paper›PMID 39770604›Full record

ArticleMicroorganisms2024

An Easy-to-Use Tool to Predict SARS-CoV-2 Risk of Infection in Closed Settings: Validation with the Use of an Individual-Based Monte Carlo Simulation.

Benedetta Santoro, Francesca Larese Filon, Edoardo Milotti

Abstract read
In one paragraph

Article in Microorganisms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Benedetta SantoroPhysics Department, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0001-7900-1783
Francesca Larese FilonOccupational Medicine Department, University Hospital of Trieste, 34129 Trieste, Italy.ORCID 0000-0002-7717-0417
Edoardo MilottiPhysics Department, University of Trieste, 34127 Trieste, Italy.ORCID 0000-0001-7348-9765

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The dynamics of the SARS-CoV-2 pandemic showed that closed environments, such as hospitals and schools, are more likely to host infection clusters due to environmental variables like humidity, ventilation, and overcrowding. This study aimed to validate our local transmission model by reproducing the data on SARS-CoV-2 diffusion in a hospital ward. We implemented our model in a Monte Carlo procedure that simulates the contacts between patients and healthcare workers in Trieste's geriatric ward and calculates the number of infected individuals. We found the median number of infected workers to be 38.98 (IQR = 7.75), while all patients were infected in most of the simulation runs. More infections occurred in rooms with lower volumes. Higher ventilation and mask-wearing contribute to reduced infections; in particular, we obtained a median value of 35.06 (IQR = 9.21) for the simulation in which we doubled room ventilation and 26.12 (IQR = 10.33) in the simulation run in which workers wore surgical masks. We managed to reproduce the data on infections in the ward; using a sensitivity analysis, we identified the parameters that had the greatest impact on the probability of transmission and the size of the outbreak.

Indexed as

closed settingdiffusionhospital settingmodel validationMonte Carlorisk evaluationSARS-CoV-2

Identifiers

PMID39770604
PMCPMC11678045

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.