Evidence map›Paper›PMID 39770426›Full record

ReviewPharmaceuticals (Basel, Switzerland)2024

Danaparoid-Consensus Recommendations on Its Clinical Use.

Rupert M Bauersachs, Edelgard Lindhoff-Last, Robert Klamroth, Andreas Koster, Marc Schindewolf, Harry Magnani

Abstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Neck-vein thrombosis during spaceflight.British journal of clinical pharmacology · 2026
    Review
  4. Anti-Platelet factor 4 immunothrombosis-not just heparin and vaccine triggers.Research and practice in thrombosis and haemostasis · 2025
    Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rupert M BauersachsCardioangiology Center Bethanien, Vascular Center and Coagulation Center, Im Prüfling 23, 60389 Frankfurt, Germany.ORCID 0000-0001-6192-1741
Edelgard Lindhoff-LastCardioangiology Center Bethanien, Vascular Center and Coagulation Center, Im Prüfling 23, 60389 Frankfurt, Germany.ORCID 0000-0002-7019-7887
Robert KlamrothDepartment Angiology and Haemostaseology, Vivantes Klinikum Friedrichsheim, Landsberger Allee 49, Friedrichshain, 10249 Berlin, Germany.
Andreas KosterDepartment of Cardio-Anaesthesiology, Sana-Herzzentrum Cottbus GmbH, Leipziger Straße 50, 03048 Cottbus, Germany.
Marc SchindewolfDivision of Angiology, Swiss Cardiovascular Center, Inselspital, Bern University Hospital, University of Bern, CH-3010 Bern, Switzerland.
Harry MagnaniIndependent Researcher, 5345 MT Oss, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

(1) Background: Danaparoid sodium is a heparinoid antithrombotic that has been used for over 40 years for prophylaxis of DVT in non-HIT patients and for the treatment of heparin-induced thrombocytopenia (HIT) with and without thrombosis. This update summarises current information on its pharmacology and reviews danaparoid dose management in a broad spectrum of clinical situations, including off-label indications. (2) Methods: Evidence from published clinical studies, case reports, compassionate use of danaparoid, and spontaneously reported serious adverse events is summarised and analysed by an interdisciplinary expert group to develop a consensus on dosing regimens of danaparoid for complex clinical situations, including vulnerable patient populations. (3) Results: Dosing regimens are proposed, together with monitoring recommendations and target anti-factor Xa ranges. (4) Conclusion: In a comprehensive summary detailed interdisciplinary dosing recommendations are described to provide a basis for safe and effective use of danaparoid.

Indexed as

anticoagulantdanaparoiddosingheparin-induced thrombocytopeniaheparinoidmonitoringoff-label useOrgaranthromboprophylaxisvenous thromboembolism

Identifiers

PMID39770426
PMCPMC11677338

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.