Evidence map›Paper›PMID 39770324›Full record

ArticlePathogens (Basel, Switzerland)2024

Clinical Utility of Induced Sputum and Bronchoalveolar Lavage Cultures in Diagnosing Nontuberculous Mycobacterial Pulmonary Disease.

Maria Angela Licata, Paola Mencarini, Annelisa Mastrobattista, Serena Maria Carli, Carlotta Cerva, Silvia Mosti, Raffaella Libertone, Alberto Zolezzi, Pietro Vittozzi, Carla Nisii and 8 more

Registry-linked trialAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07232550 (Biomarkers and Respiratory Omics as New CHildren Opportunities - Study of Clinical Outcomes and Predictivity Evaluation - a Multi-cohort, Multi-center Study), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07232550 recruitingnot on this mapstarted 2026, after this paper: background citation

Biomarkers and Respiratory Omics as New CHildren Opportunities - Study of Clinical Outcomes and Predictivity Evaluation - a Multi-cohort, Multi-center Study

TypeobservationalSponsorMedical University of WarsawRan2026 to 2035Enrolled160ConditionsAsthma in Children, Protracted Bacterial Bronchitis, Chronic CoughArmsfiberoptic bronchoscopy, blood sample collection, Respiratory functional tests, Sputum culture
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. TheFrontiers in medicine · 2026
    Article
  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Maria Angela LicataRespiratory Infectious Diseases Unit, National Institute for Infectious Diseases "Lazzaro Spallanzani" IRCCS, 00149 Rome, Italy.ORCID 0000-0001-6238-3818
Paola MencariniRespiratory Infectious Diseases Unit, National Institute for Infectious Diseases "Lazzaro Spallanzani" IRCCS, 00149 Rome, Italy.ORCID 0000-0001-8928-8183
Annelisa MastrobattistaRespiratory Infectious Diseases Unit, National Institute for Infectious Diseases "Lazzaro Spallanzani" IRCCS, 00149 Rome, Italy.
Serena Maria CarliRespiratory Infectious Diseases Unit, National Institute for Infectious Diseases "Lazzaro Spallanzani" IRCCS, 00149 Rome, Italy.
Carlotta CervaRespiratory Infectious Diseases Unit, National Institute for Infectious Diseases "Lazzaro Spallanzani" IRCCS, 00149 Rome, Italy.
Silvia MostiRespiratory Infectious Diseases Unit, National Institute for Infectious Diseases "Lazzaro Spallanzani" IRCCS, 00149 Rome, Italy.
Raffaella LibertoneRespiratory Infectious Diseases Unit, National Institute for Infectious Diseases "Lazzaro Spallanzani" IRCCS, 00149 Rome, Italy.
Alberto ZolezziRespiratory Infectious Diseases Unit, National Institute for Infectious Diseases "Lazzaro Spallanzani" IRCCS, 00149 Rome, Italy.
Pietro VittozziRespiratory Infectious Diseases Unit, National Institute for Infectious Diseases "Lazzaro Spallanzani" IRCCS, 00149 Rome, Italy.
Carla NisiiDepartment of Microbiology, National Institute for Infectious Diseases "Lazzaro Spallanzani" IRCCS, 00149 Rome, Italy.ORCID 0000-0001-5369-0437
Antonio MazzarelliDepartment of Microbiology, National Institute for Infectious Diseases "Lazzaro Spallanzani" IRCCS, 00149 Rome, Italy.ORCID 0000-0001-6285-4368
Angela CannasDepartment of Microbiology, National Institute for Infectious Diseases "Lazzaro Spallanzani" IRCCS, 00149 Rome, Italy.
Assunta NavarraDepartment of Epidemiology, National Institute for Infectious Diseases "Lazzaro Spallanzani" IRCCS, 00149 Rome, Italy.ORCID 0000-0002-3662-4312
Stefania IannielloDiagnostic Imaging Unit for Infectious Diseases, National Institute for Infectious Diseases "Lazzaro Spallanzani" IRCCS, 00149 Rome, Italy.
Rocco TrisoliniInterventional Pulmonology Division, Fondazione Policlinico Universitario "Agostino Gemelli" IRCCS, 00136 Rome, Italy.ORCID 0000-0002-1067-4696
Delia GolettiTranslational Research Unit, National Institute for Infectious Diseases (INMI), "Lazzaro Spallanzani" IRCCS, 00149 Rome, Italy.ORCID 0000-0001-8360-4376
Fabrizio PalmieriRespiratory Infectious Diseases Unit, National Institute for Infectious Diseases "Lazzaro Spallanzani" IRCCS, 00149 Rome, Italy.ORCID 0000-0001-8184-6291
Gina GualanoRespiratory Infectious Diseases Unit, National Institute for Infectious Diseases "Lazzaro Spallanzani" IRCCS, 00149 Rome, Italy.

Funding

Italian Ministry of Health, with the "Ricerca Corrente" grant of the IRCCS Research Program n.4 Tuberculosis
6 · The paper itself

Abstract

Diagnosing non-tuberculous mycobacterial pulmonary disease (NTM-PD) in patients unable to produce sputum spontaneously requires invasive procedures to obtain valid respiratory specimens. In this retrospective study, we evaluated the results of microbiological tests performed on respiratory samples of 132 patients affected by NTM-PD. In the diagnostic workout, 98 patients performed both induced sputum (IS) and bronchoalveolar lavage (BAL) and were enrolled in our study. A total of 93 out of 98 BAL samples (95%) were culture-positive for mycobacteria, whereas only 67/153 (44%) induced sputum cultures were positive for NTM (

Indexed as

Bronchoalveolar Lavage FluidMycobacterium Infections, NontuberculousNontuberculous MycobacteriaSputumAdultAgedAged, 80 and overFemaleHumansLung DiseasesMaleMiddle AgedReal-Time Polymerase Chain ReactionRetrospective Studiesbronchoalveolar lavage (BAL)induced sputum (IS)nontuberculous mycobacterial pulmonary disease (NTM-PD)non-tuberculous mycobacteria (NTM) culturereal-time polymerase chain reaction (PCR)

Identifiers

PMID39770324
PMCPMC11728528

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.