Evidence map›Paper›PMID 39770138›Full record

ArticleMolecules (Basel, Switzerland)2024

Novel 4-alkoxy Meriolin Congeners Potently Induce Apoptosis in Leukemia and Lymphoma Cells.

Karina S Krings, Tobias R Wassenberg, Pablo Cea-Medina, Laura Schmitt, Ilka Lechtenberg, Tanya R Llewellyn, Nan Qin, Holger Gohlke, Sebastian Wesselborg, Thomas J J Müller

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Karina S KringsInstitute for Molecular Medicine I, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Universitätsstraße 1, D-40225 Düsseldorf, Germany.ORCID 0000-0001-6519-1395
Tobias R WassenbergInstitute of Organic Chemistry and Macromolecular Chemistry, Faculty of Mathematics and Natural Sciences, Heinrich Heine University Düsseldorf, Universitätsstraße 1, D-40225 Düsseldorf, Germany.
Pablo Cea-MedinaInstitute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, Universitätsstraße 1, D-40225 Düsseldorf, Germany.
Laura SchmittInstitute for Molecular Medicine I, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Universitätsstraße 1, D-40225 Düsseldorf, Germany.
Ilka LechtenbergInstitute for Molecular Medicine I, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Universitätsstraße 1, D-40225 Düsseldorf, Germany.ORCID 0000-0001-6124-1885
Tanya R LlewellynDepartment of Hematology, Oncology and Clinical Immunology, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Moorenstraße 5, D-40225 Düsseldorf, Germany.
Nan QinDepartment of Hematology, Oncology and Clinical Immunology, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Moorenstraße 5, D-40225 Düsseldorf, Germany.
Holger GohlkeInstitute for Pharmaceutical and Medicinal Chemistry, Heinrich Heine University Düsseldorf, Universitätsstraße 1, D-40225 Düsseldorf, Germany.ORCID 0000-0001-8613-1447
Sebastian WesselborgInstitute for Molecular Medicine I, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University Düsseldorf, Universitätsstraße 1, D-40225 Düsseldorf, Germany.ORCID 0000-0002-5236-942X
Thomas J J MüllerInstitute of Organic Chemistry and Macromolecular Chemistry, Faculty of Mathematics and Natural Sciences, Heinrich Heine University Düsseldorf, Universitätsstraße 1, D-40225 Düsseldorf, Germany.ORCID 0000-0001-9809-724X

Funding

Deutsche Forschungsgemeinschaft 270650915/GRK 2158Deutsche Forschungsgemeinschaft 417677437/GRK 2578Düsseldorf School of Oncology n/aFonds der Chemischen Industrie n/a
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ApoptosisLeukemiaLymphomaAntineoplastic AgentsCell Line, TumorHumansJurkat CellsAntineoplastic Agents7-azaindolesapoptosis inducersbiheteroarylscyclin dependent kinases (CDK)leukemia cell lineslymphoma cell linesmeriolinsone-pot synthesispalladium catalysisSuzuki coupling

Identifiers

PMID39770138
PMCPMC11676355

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.