Clearance of Intracellular Pathogens with Hyaluronic Acid Nanomicelles Responsive to H

Jun Luo, Hui Huang, Junfeng Jiang, Wenyu Zheng, Peng Chen, Hongjin Bai

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jun LuoEngineering Laboratory of Chemical Resources Utilization in South Xinjiang, Tarim University, Alar 843300, China.

Hui HuangEngineering Laboratory of Chemical Resources Utilization in South Xinjiang, Tarim University, Alar 843300, China.

Junfeng JiangEngineering Laboratory of Chemical Resources Utilization in South Xinjiang, Tarim University, Alar 843300, China.

Wenyu ZhengEngineering Laboratory of Chemical Resources Utilization in South Xinjiang, Tarim University, Alar 843300, China.

Peng ChenEngineering Laboratory of Chemical Resources Utilization in South Xinjiang, Tarim University, Alar 843300, China.

Hongjin BaiEngineering Laboratory of Chemical Resources Utilization in South Xinjiang, Tarim University, Alar 843300, China.

Funding

Tarim University TDZKCX202302the Science and Technology Guidance Plan Project 2023ZD096

6 · The paper itself

Abstract

Hyaluronic acid (HA) is an acidic mucopolysaccharide of animal origin composed of repeating disaccharide units of N-acetylglucosamine and glucuronic acid. Due to its excellent biocompatibility, biodegradability, and selective affinity for CD44 receptors on cell surfaces, HA is widely employed as a drug carrier. In our study, we aimed to target subcellular bacteria by grafting cystamine onto HA scaffolds through an amide reaction, producing a linker responsive to H

Indexed as

Anti-Bacterial AgentsHyaluronic AcidMicellesAnimalsBiofilmsDrug CarriersHumansHydrogen-Ion ConcentrationMiceNanoparticlesTriclosanAnti-Bacterial AgentsDrug CarriersHyaluronic AcidMicellesTriclosanbiofilmhyaluronic acidintracellular bacteriapH and H2S dual-responsive

Identifiers

PMID39770059

DOI10.3390/molecules29245971

PMCPMC11678907

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.