β,β-Difluoro Peroxides as Fluorinated C2-Building Blocks for the Construction of Functionalized Indolizines.

Yangyang Ma, Hua Zhang, Xiaoxiao Du, Shurui Fang, Kexin Yin, Gangfeng Du, Zhengshan Tian, Zhonghao Zhou

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Facile Synthesis of Polysubstituted Pyridines via Metal-Free [3+3] Annulation Between Enamines and β,β-Dichloromethyl Peroxides.International journal of molecular sciences · 2025
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yangyang MaSchool of Chemical & Environmental Engineering, Pingdingshan University, Pingdingshan 467000, China.

Hua ZhangCollege of Medicine, Pingdingshan University, Pingdingshan 467000, China.

Xiaoxiao DuSchool of Chemical & Environmental Engineering, Pingdingshan University, Pingdingshan 467000, China.

Shurui FangSchool of Chemical & Environmental Engineering, Pingdingshan University, Pingdingshan 467000, China.

Kexin YinSchool of Chemical & Environmental Engineering, Pingdingshan University, Pingdingshan 467000, China.

Gangfeng DuSchool of Chemical & Environmental Engineering, Pingdingshan University, Pingdingshan 467000, China.

Zhengshan TianSchool of Chemical & Environmental Engineering, Pingdingshan University, Pingdingshan 467000, China.

Zhonghao ZhouSchool of Material Science and Engineering, Dalian Jiaotong University, Dalian 116028, China.

Funding

Doctoral Scientific Research Foundation of Pingdingshan University PXY-BSQD-2023002Henan Province science and technology research project 242102230037Key Scientific Programs of Higher Education of Henan Province of China 24B150024Natural Science Foundation of Henan Province of China 242300420568

6 · The paper itself

Abstract

An effective method for the construction of functionalized indolizines has been developed in which β,β-difluoro peroxides act as novel C2-building blocks to implement [3+2] annulation with pyridinium ylides under base-mediated conditions. With this protocol, a broad range of multisubstituted indolizines were prepared in moderate to good yields under mild conditions, and many useful functional groups were tolerated.

Indexed as

fluorinated C2-building blocksfunctionalized indolizinesβ,β-difluoro peroxides

Identifiers

PMID39770016

DOI10.3390/molecules29245927

PMCPMC11676711

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