Evidence map›Paper›PMID 39769383›Full record

ArticleInternational journal of molecular sciences2024

Antitumor Activity and Multi-Target Mechanism of Phenolic Schiff Bases Bearing Methanesulfonamide Fragments: Cell Cycle Analysis and a Molecular Modeling Study.

Alaa A-M Abdel-Aziz, Adel S El-Azab, Simone Brogi, Rezk R Ayyad, Ibrahim A Al-Suwaidan, Mohamed Hefnawy

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alaa A-M Abdel-AzizDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.ORCID 0000-0002-3362-9337
Adel S El-AzabDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Simone BrogiDepartment of Pharmacy, University of Pisa, Via Bonanno 6, 56126 Pisa, Italy.ORCID 0000-0001-9375-6242
Rezk R AyyadDepartment of Pharmaceutical Chemistry, College of Pharmacy, University of Hilla, Babylon 6202, Iraq.
Ibrahim A Al-SuwaidanDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.
Mohamed HefnawyDepartment of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, P.O. Box 2457, Riyadh 11451, Saudi Arabia.

Funding

The authors extend their appreciation to the Researchers Supporting Project number (RSPD2024R1049), King Saud University, Riyadh, Saudi Arabia, for funding this research. RSPD2024R1049
6 · The paper itself

Abstract

Five phenolic Schiff bases (

Indexed as

Antineoplastic AgentsCell ProliferationErbB ReceptorsMolecular Docking SimulationSchiff BasesSulfonamidesCell CycleCell Line, TumorErb-b2 Receptor Tyrosine KinasesHumansModels, MolecularPhenolsAntineoplastic AgentsEGFR protein, humanERBB2 protein, humanErb-b2 Receptor Tyrosine KinasesErbB ReceptorsPhenolsSchiff BasesSulfonamidesantitumor activitycell cycle analysisenzymatic assaymolecular dockingmolecular dynamic simulationphenolic Schiff bases

Identifiers

PMID39769383
PMCPMC11728000

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.