Evidence map›Paper›PMID 39769268›Full record

ArticleInternational journal of molecular sciences2024

Insights into Within-Host Evolution and Dynamics of Oral and Intestinal Streptococci Unveil Niche Adaptation.

Mohamed M H Abdelbary, Maximilian Hatting, Andrea Dahlhausen, Alexandra Bott, Georg Conrads

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Whole-genome and pan-genome analyses reveal genomic differences among nontypeableFrontiers in cellular and infection microbiology · 2026
    Article
  4. Exploring the Genetic and Functional Diversity ofInternational journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Mohamed M H AbdelbaryDivision of Nosocomial Pathogens and Antibiotic Resistances, Department of Infectious Diseases, Robert Koch Institute, Wernigerode Branch, 38855 Wernigerode, Germany.
Maximilian HattingDepartment of Medicine III, RWTH University Hospital, 52074 Aachen, Germany.
Andrea DahlhausenUniversity Medical Center for Occupational Medicine, RWTH University, 52074 Aachen, Germany.
Alexandra BottDivision of Oral Microbiology and Immunology, Department of Operative Dentistry, Periodontology and Preventive Dentistry, Rheinisch-Westfälische Technische Hochschule (RWTH) University Hospital, 52074 Aachen, Germany.
Georg ConradsDivision of Oral Microbiology and Immunology, Department of Operative Dentistry, Periodontology and Preventive Dentistry, Rheinisch-Westfälische Technische Hochschule (RWTH) University Hospital, 52074 Aachen, Germany.ORCID 0000-0003-2577-5294

Funding

RWTH Aachen University Hospital IZKF project OC1-6RWTH Aachen University Hospital STREPTORANTES #109/19
6 · The paper itself

Abstract

The oral-gut axis is a complex system linking the oral cavity and gastrointestinal tract, impacting host health and microbial composition. This study investigates genetic changes and adaptive mechanisms employed by streptococci-one of the few genera capable of colonizing oral and intestinal niches-within the same individual. We conducted whole-genome sequencing (WGS) on 218 streptococcal isolates from saliva and fecal samples of 14 inflammatory bowel disease (IBD) patients and 12 healthy controls. Our analysis identified 16 streptococcal species, with

Indexed as

Genome, BacterialMouthStreptococcusAdaptation, PhysiologicalAdultEvolution, MolecularFecesFemaleGastrointestinal MicrobiomeHumansInflammatory Bowel DiseasesIntestinesMalePhylogenyPolymorphism, Single NucleotideSalivainflammatory bowel diseasemobile genetic elementsmutational spectrumoral–gut axisrecombinationstreptococciwithin-host evolution

Identifiers

PMID39769268
PMCPMC11727833

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.